Freezing of gait in Parkinson's disease: The impact of dual‐tasking and turning

Abstract

360° turning in combination with a dual-task is the most important trigger for freezing. During turning, non-freezers and controls decreased their cadence whereas freezers increased it, which may be related to FOG. Freezers adopted a posture second strategy in contrast to non-freezers when confronted with a dual task.

Loss of gait control assessed by cognitive-motor dual-tasks: pros and cons in detecting people at risk of developing Alzheimer’s and Parkinson’s diseases

“…As for AD, dual-taskrelated gait changes in the clinical phase of PD is clinically relevant to detect patients at risk of falls. Also, some studies have shown that dual-task walking performance was associated with gait quality (Kelly et al 2012), freezing (Spildooren et al 2010), disease severity, and disability (Fuller et al 2013). Hollman et al 2011 andLord et al 2013 (pace, rhythm, phases, asymmetry, variability, andpostural control), and arm swing parameters inspired from Mirelman et al 2016 (amplitude, variability, and Dual-task-related gait changes: comparison between AD and PD at the clinical stage Even though the neuropathological origin of dual-task-related gait changes is different between the two diseases, the corresponding gait patterns display some similarities, particularly in the pace, rhythm, postural control, and variability domains of gait.…”

Clinical and Genetic Aspects in Patients with Idiopathic Parkinson Disease

“…In their patients, this instability is seen through partial walking instability in the initial disease stadium and as freezing phenomena in the advanced disease stadiums. According to them, the freezing phenomena are often expressed in simultaneous double activities and in the act of turning after short walking [13]. Kerstin Ziegler and all.…”

Neuromuscular correlates of subthalamic stimulation and upper limb freezing in Parkinson’s disease

“…We introduced dual task interference, in order to reliably obtain freezing episodes under research laboratory conditions (Camicioli et al, 1998;O'Shea et al, 2002;Spildooren et al, 2010). StimOn was considered as therapeutic condition, as we aimed to capture ULF resistant to subthalamic stimulation therapy as a widely recognized limitation of PD state-of-the-art therapy in advanced disease stages (Krack et al, 2003;Vercruysse et al, 2014;Weiss et al, 2013).…”

“…We hypothesized that iPD show increased intermuscular coherence in StimOff, and we postulated that subthalamic stimulation would decrease it. Second, we introduced additional dual task interference in the StimOn condition in order to provoke freezing phenomena, i.e., ULF (Spildooren et al, 2010). We selected StimOn in order to capture freezing episodes resistant to STN-DBS therapy.…”