Free T4 in plasma. Usefulness for monitoring thyroid replacement therapy

Abstract

Department o f P e d i a t r i c s , U n i v e r s i t y o f Wessina, I t a l y . Changes i n t h y r o i d economy induced by carbamazepine (CBZ) therapy i n L-14 substit u t e d hypothyroid c h i l d r e n . CBZ treatment i s known t o decrease serum t h y r o i d hormone t i t e r s , u i t h o u t g e n e r a l l y affecting TSH l e v e l s or the t h y r o i d status. The mechanism for t h i s t r a n s i e n t e eff e c t has been n o t y e t defined. I n 5 L-14 s u b s t i t u t e d hypothyroid c h i l d r e n with p a r

The Role of Maternal Autoimmune Thyroid Disease in Neonatal Hypothyroidism

“…9 Boyages et al8 also found that 60% of Chinese infants with endemic congenital hypothy¬ roidism (endemic cretinism) had TGIIg in their serum samples. The frequency with which these antibod¬ ies are found and their role in the pathogenesis of the malformation are uncertain.…”