Free running asthma screening test.

Tsanakas, John; Milner, Ross; Bannister, O M; Boon, A W

doi:10.1136/adc.63.3.261

Cited by 57 publications

(28 citation statements)

References 12 publications

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“…This is lower than the 50-70% incidence among known or current asthmat ics found in other similar studies [1][2][3][4], It seems un likely that medication use has a significant effect in this study as no inhaled medicine was allowed at least 3 h prior to testing, and only 2 of the asthmatic nonre sponders were on theophylline. One of these individu als was also on inhaled corticosteroids.…”

Section: Discussioncontrasting

confidence: 49%

mentioning

confidence: 99%

“…As a result, a free-running 6-min screening test has been proposed as a means of facili tating diagnosis and treatment [1,2]. In several studies where EIA was defined as a decrease in peak expira tory flow rate (PEFR) exceeding 15% following 6 min of free running, the prevalence of EIA among known asthmatics varied from 50 to 70% [1][2][3][4]]. EIA can also be demonstrated in some children with allergic rhini tis and no clinical asthma [5,6], and the maximum fall in postexercise PEFR in normal children has varied from 12.5% [7] to 15% [3].…”

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confidence: 99%

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Exercise-Induced Asthma in Adolescent Gym Class Population

Bransford

McNutt²,

Fink³

1991

Int Arch Allergy Immunol

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The prevalence of exercise-induced asthma (ElA) was determined in a population of 12- and 13-year-old schoolchildren whose parents returned a questionnaire regarding a previous diagnosis of asthma, recent asthmatic symptoms and symptoms of allergic rhinitis. El A was defined as a >15% fall in peak expiratory flow rate (PEFR) following 6 min of free running in a gymnasium. Among the 201 children studied, 18 (8.9%) demonstrated El A. Of 21 children with symptomatic asthma in the 6 months prior to study, 9 (43%) developed El A compared to none of 6 children with asymptomatic asthma (p <0.0001). Among 48 children with a history of allergic rhinitis alone, 7 (14.6%) demonstrated El A. The mean postexercise changes in PEFR were 14.9% for 16 children with both asthma and allergic rhinitis, 6.4% among 48 children with allergic rhinitis only, and 1.8% among 125 normal children. Recent symptoms of asthma and a history of allergic rhinitis appeared to be risk factors for EIA. EIA was readily demonstrated in a gym class setting; the use of such screening may facilitate its diagnosis and treatment.

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Section: Discussioncontrasting

confidence: 49%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Exercise-Induced Asthma in Adolescent Gym Class Population

Bransford

McNutt²,

Fink³

1991

Int Arch Allergy Immunol

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“…It is currently accepted that, with few exceptions, the prevalence of asthma in children varies between 7 and 10% [11,12], depending on local factors. In England, WILLIAMS et al [13], using free running as the exercise test, reported a prevalence of exercise-induced asthma of 13%; whereas, in Denmark, HOST et al [14] found a prevalence of 7.2%.…”

mentioning

confidence: 99%

Prevalence of asthma-related symptoms and bronchial responsiveness to exercise in children aged 13-14 yrs in Barcelona, Spain

Busquets

Antó²,

Sunyer³

et al. 1996

Eur Respir J

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It is not clear whether asymptomatic bronchial responsiveness is a risk factor for development of asthma. A cross-sectional study was conducted to determine the prevalence of asthma among schoolchildren from Barcelona (Spain). The association between respiratory symptoms and bronchial responsiveness to exercise was examined. For this study 3,033 schoolchildren aged 13-14 yrs were studied from the general population. Participants answered a respiratory questionnaire and a self-reporting video-questionnaire. A total of 2,842 children underwent bronchial responsiveness testing by exercise challenge. The study was part of the International Study of Asthma and Allergies in Childhood (ISAAC) project. The prevalence of "current asthma" (recent wheezing and bronchial responsiveness to exercise) was 4% and the prevalence of "wheezing only" 10%. A fall in peak expiratory flow rate (PEFR) > or = 15% after exercise testing was found in 324 (11%) children, 29 (9%) of whom presented clinical symptoms of asthma. Bronchial responsiveness to exercise was significantly associated with all items of the asthma questionnaire. The prevalence of asthma-related symptoms in this inner-city area was lower than frequently reported rates in other countries, although the prevalence of exercise-induced bronchoconstriction was relatively high, and threefold greater than in a geographical area in the vicinity of Barcelona. These findings are consistent with the current view that asthma-related symptoms and bronchial responsiveness to exercise have different meanings in a community survey, and that local environmental factors could influence the prevalence of bronchial responsiveness.

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“…The discrepancy in the results of the two airway challenges may be due to a greater sensitivity of methacholine for asthma (31) or differing mechanisms (32) and risk factors (33) for these markers of airway function. Although misclassification of the children by the exercise test is a possibility, care was taken to standardize the test (18). Thirty-nine children performed exercise tests on two different days, on average, 30 days apart.…”

Section: P<005mentioning

confidence: 99%

Birthweight and Preterm Birth in Relation to Indicators of Childhood Asthma

Demissie

Ernst

Joseph

et al. 1997

Canadian Respiratory Journal

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BACKGROUND: Early life events may have long term consequences on respiratory health including the risk of developing asthma. OBJECTIVE: To examine the independent roles of birthweight and preterm birth on childhood asthma after accounting for socioeconomic status. METHODS: A total of 989 elementary school children performed spirometry before and after a free-running exercise challenge. A subsample of 327 children underwent methacholine bronchoprovocation and allergy skin prick tests to common inhaled aeroallergens. Information on birthweight and preterm birth was obtained by parental interview. Socioeconomic status was established using parental occupation. RESULTS: After adjusting for the effects of important confounding variables, birthweight was positively associated with forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1); FVC increased 4.5% per kg (95% CI 1.7 to 7.4) and FEV1 4.4% per kg (95% CI 1.8 to 7.2). Birthweight was not related to exercise-induced bronchospasm or an asthma diagnosis, but airway responsiveness to methacholine increased as birthweight decreased (P=0.01). Preterm birth independent of birthweight was associated with a lower FEV 1 /FVC (-1.7%; 95% CI -2.8 to -0.5).CONCLUSIONS: Birthweight appears to be related to lung size and methacholine responsiveness while preterm birth appears to diminish airway size.

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Free running asthma screening test.

Cited by 57 publications

References 12 publications

Exercise-Induced Asthma in Adolescent Gym Class Population

Exercise-Induced Asthma in Adolescent Gym Class Population

Prevalence of asthma-related symptoms and bronchial responsiveness to exercise in children aged 13-14 yrs in Barcelona, Spain

Birthweight and Preterm Birth in Relation to Indicators of Childhood Asthma

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