One of the factors for the development and spread of antibacterial resistance of bacteria is untimely or incorrectly performed laboratory diagnostics, which results in randomly prescribed antibacterial therapy aimed at containing the infection and ensuring the safety of the livestock. This phenomenon is common in many industrial poultry and livestock enterprises, but at the same time, it is difficult to blame the veterinary service of these farms, since they must ensure safety which sometimes cannot be achieved without antibiotics. The use of advanced microbiological screening of all microbiological risks to which enterprises are exposed is proposed as means of solving the indicated problem. The results of such work done in a number of duck breeding enterprises in Russia, in which at least 192 species of cultivated bacteria are circulated, are presented as an example. Most of the isolated microbes are representatives of the normal or transient flora, but a certain part of the bacteria has an obvious pathogenic or conditionally pathogenic role. From the selected bacteria, we emphasize the relevance of the following pathogens for the duck breeding industry: Bordetella avium, Campylobacter coli, Campylobacter concisus, Campylobacter jejuni, Clostridium colinum, Clostridium perfringens, Myroides odoratimimus, Pasteurella multocida, Riemerella anatipestifer, Salmonella typhimurium, Staphylococcus aureus, Staphylococcus haemolyticus, Streptococcus pneumoniae, Streptococcus entericus, Streptococcus gallolyticus, Shigella sonnei, which are typical pathogens of poultry infections. Information from the literature about the remaining bacteria were analyzed and structured in the form of a table with the description of the possible clinical and morphological manifestations of the diseases that they cause.