Free radical scavenging and antibacterial activities of Malaysian guttiferae plants

Susanti, Deny; Taher, Muhammad; Attoumani, Nissad; Ahmad, Farediah

doi:10.5897/jmpr11.678

Cited by 6 publications

(5 citation statements)

References 7 publications

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“…Pearson correlation coe cients between radical scavenging activity (%) and phytochemical contentIn terms of radical scavenging activity (RSA), the n-hexane extract exhibited the lowest activity (2.65 ± 1.19 %) consistent with previous ndings indicating a higher half response concentration (RC 50 85 ± 4.35 µg/mL) compared to the methanol extract(Alkhamaiseh et al 2012) (Susanti et al 2011…”

supporting

confidence: 87%

Antioxidant Potential of Calophyllum canum P. F. Stevens: Xanthones, Phenolics, and Radical Scavenging Activity

Lizazman,

Mian

2024

Preprint

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The isolation and purification of the ethyl acetate of C. canum stem bark have yielded a new α,β-unsaturated δ-lactone compound, canumolactone (8), along with known xanthones, 1-hydroxy-7-methoxyxanthone (1), caloxanthone C (2), trapezifolixanthone (3), ananixanthone (4), euxanthone (5), gentisin (6), 2-hydroxyxanthone (7), and α-mangostin (9). In this study on C. canum extracts, the total phenolic content (TPC), total flavonoid content (TFC), and radical scavenging activity (RSA) were investigated to assess the antioxidant potential. The extraction of C. canum stem bark yielded various crude extracts, with the ethyl acetate extract showing the highest RSA (97.14 ± 0.24 %) and TPC (277.33 ± 9.65 mg GAE/g extract). The TFC values varied across extracts, with the dichloromethane extract displaying the highest TFC (117.96 ± 3.35 mg QE/g extract). A strong positive correlation was observed between TPC and RSA, indicating the significant role of phenolic compounds in the antioxidant activity of the extracts. Conversely, the relationship between TFC and RSA was weak, suggesting a minor contribution of flavonoids to the antioxidant potential of the extracts. These findings highlight the importance of phenolic compounds in determining the antioxidant activity of C. canum extracts.

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supporting

confidence: 87%

Antioxidant Potential of Calophyllum canum P. F. Stevens: Xanthones, Phenolics, and Radical Scavenging Activity

Lizazman,

Mian

2024

Preprint

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“…The above assigned structure (II) was further confirmed by the bromination of 12,20diene (I) followed by Jon's oxidation and debromination. The final product so obtained was found to be completely similar with that of Lup-12,20dien 3-one (m.p., m.m.p, Rf value and co-TLC).…”

Section: O ( I I )mentioning

confidence: 64%

“…The melting point agreed with that of friedelin. Its identity as friedelin (III) was established by comparison of its 1 H-NMR (Table -3), ir and mass spectra (with an authentic sample [12][13][14] of friedelin.…”

Section: Compound (3)mentioning

confidence: 99%

Extraction, Isolation and Characterization of Valuable Worked on Acacia Tortilis

Muhaisen

2021

Egypt. J. Chem.

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Acacia tortilis is one of the important species of genus Acacia belonging to family Leguminaceae. Though there is no more study performed on this plant but it plays important role in the countries where it found. These countries include North Africa, Arabian Peninsula and Asian countries. The various part of Acacia tortilis plant say leaves, pods, gum exudates and bark were used as antidiabetic, antidiarrhoeal, antiasthmatic and also had several other medicinal benefits. The present discussion deals with the isolation and characterization of the following compounds from the leaves of Acacia tortilis.

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“…Scanning electron microscope has been done on the cells after treatment with 1 and 5 as shown in Figure 2. Both compounds induced apoptosis on H1299 and A549 indicated by blebbing phenomenon, a specific pattern on apoptosis (27). Cytotoxic activity has also been observed in derivatives of linear squalene.…”

Section: Resultsmentioning

confidence: 80%

Cytotoxicity of triterpenes from the leaves of Garcinia prainiana King (Guttiferae)

Salleh

Ahmad

et al. 2016

Marmara Pharmaceutical Journal

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Free radical scavenging and antibacterial activities of Malaysian guttiferae plants

Cited by 6 publications

References 7 publications

Antioxidant Potential of Calophyllum canum P. F. Stevens: Xanthones, Phenolics, and Radical Scavenging Activity

Antioxidant Potential of Calophyllum canum P. F. Stevens: Xanthones, Phenolics, and Radical Scavenging Activity

Extraction, Isolation and Characterization of Valuable Worked on Acacia Tortilis

Cytotoxicity of triterpenes from the leaves of Garcinia prainiana King (Guttiferae)

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