“…SNPs with particle sizes ranging from 20 nm to 6 μm can be produced through chemical pathways (e.g., reactive extrusion, emulsion precipitation) or physical treatments (e.g., microfluidization, ultrasonication). − To explore more exciting possibilities of SNP-based materials, further modification of SNPs has proven necessary. , There are generally two types of approaches to modify SNPs: via small molecule chemistry and via polymerization. Small molecule chemistry approaches are normally achieved by introducing various moieties, e.g., esters, ethers, and anhydrides. − Modification of SNPs through polymerization involves “grafting from” and “grafting to” techniques and can be performed using free radical polymerization, living/controlled radical polymerization, ring-opening polymerization, etc. ,− …”