Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum

Xu, Ming; Deng, GuiFu; Liu, Shanshan; Chen, Shuo; Cui, Dan Feng; Yang, Limin; Wang, Qiuquan

doi:10.1039/c005387m

Cited by 43 publications

(19 citation statements)

References 25 publications

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“…Indeed, other authors have attributed observed toxicity to metal ions leaching from the QDs core [34,[70][71][72][73]. Similar results were also reported by Benavides et al [11] after exposing C. auratus to AlO 3 and ZnO nanoparticles (NPs).…”

Section: Discussionsupporting

confidence: 74%

Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio)

Matos

Martins

Cid‐Samamed

et al. 2019

IJERPH

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The exponential growth of nanotechnology has led to the production of large quantities of nanomaterials for numerous industrial, technological, agricultural, environmental, food and many other applications. However, this huge production has raised growing concerns about the adverse effects that the release of these nanomaterials may have on the environment and on living organisms. Regarding the effects of QDs on aquatic organisms, existing data is scarce and often contradictory. Thus, more information is needed to understand the mechanisms associated with the potential toxicity of these nanomaterials in the aquatic environment. The toxicity of QDs (ZnS and CdS) was evaluated in the freshwater fish Danio rerio. The fishes were exposed for seven days to different concentrations of QDs (10, 100 and 1000 µg/L) individually and combined. Oxidative stress enzymes (catalase, superoxide dismutase and glutathione S-transferase), lipid peroxidation, HSP70 and total ubiquitin were assessed. In general, results suggest low to moderate toxicity as shown by the increase in catalase activity and lipid peroxidation levels. The QDs (ZnS and CdS) appear to cause more adverse effects singly than when tested combined. However, LPO results suggest that exposure to CdS singly caused more oxidative stress in zebrafish than ZnS or when the two QDs were tested combined. Levels of Zn and Cd measured in fish tissues indicate that both elements were bioaccumulated by fish and the concentrations increased in tissues according to the concentrations tested. The increase in HSP70 measured in fish exposed to 100 µg ZnS-QDs/L may be associated with high levels of Zn determined in fish tissues. No significant changes were detected for total ubiquitin. More experiments should be performed to fully understand the effects of QDs exposure to aquatic biota.

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Section: Discussionsupporting

confidence: 74%

Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio)

Matos

Martins

Cid‐Samamed

et al. 2019

IJERPH

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“…After they were exposed to CdSe/ZnS‐QDs capped by mercaptoacetic acid and 2‐mercaptopropionic acid, respectively, they observed that core/shell QDs could hardly be internalized into the plant but only were adsorbed on the plant surface. In contrast, Phaeodactylum tricornutum and rice can not only absorb the ions released by QDs but also internalize entire QDs [20,24] . However, the difference of the surface coating of QDs significantly affects the internalization of the same plant.…”

Section: Interaction Between Qds and Plantsmentioning

confidence: 99%

“…The uptake of QDs mainly includes two approaches, i) directly adsorbed by plants as particles; ii) the ions released by QDs were taken up by plants. Researchers usually reveal the uptake and accumulation of QDs by plants through fluorescence microscope, confocal microscope, inductively coupled plasma mass spectrometry, or Raman spectroscopy [18–21] . But to date, whether QDs can completely be internalized by plants is not well elucidated.…”

Section: Interaction Between Qds and Plantsmentioning

confidence: 99%

Influence of Luminescent Nanomaterials on Plant Growth and Development

Han

et al. 2021

ChemNanoMat

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As an emerging research hotspot in nanotechnology, luminescent nanomaterials (LNMs) have attracted much attention due to their unique properties. Meanwhile, their potential release into the environment has also been investigated by researchers. Plants, as an essential part of the ecosystem, are the starting point of bioaccumulation. Thus, to understand the interaction between LNMs and plants would be one of the critical aspects of risk assessment. Currently, there are still very few reports in this field, where a potential guidance is urgently necessary. Bearing this in mind, herein, based on our own research experience, we summarize the effects of four typical kinds of LNMs (quantum dots, carbon dots, upconversion nanoparticles, and metal nanoclusters) on plant growth and development, including the transport of materials in plants and their toxicity to plants, as well as the according experimental techniques. Finally, the current challenges and prospects are pointed out, thereby hoping to provide a timely fundamental guidance for future research.

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“…Alternatives such as environmental SEM/TEM which do not require vacuum in the specimen chamber and thus do not require a dry sample are currently being refi ned. Fluorescence or preferably confocal laser scanning microscopy (CLSM) are valuable to visualize fl uorescent NMs [ 48 ]. Depending on the fl uorescence wavelength emitted by the NMs, algal autofl uorescence may interfere with NM detection.…”

Section: Testing Nanomaterials Toxicity In Unicellular Eukaryotic Algamentioning

confidence: 99%

Testing Nanomaterial Toxicity in Unicellular Eukaryotic Algae and Fish Cell Lines

Kröll

Kühnel

Schirmer

2013

Oxidative Stress and Nanotechnology

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Nanoecotoxicology as a sub-discipline of ecotoxicology aims to identify and predict effects elicited on ecosystems by nano-sized materials (NM). Two key groups of model organisms in this context are algae and fi sh. In this chapter, we present considerations for testing NM with respect to their impact on unicellular algae and cell lines derived from various organs of fi sh.Based on currently available literature on NM effects in unicellular algae and fi sh cell lines, and our own experience, we provide guidance on test design, including principle test considerations, materials, NM presentation to cells, exposure, bioavailability, and effect assessment. Assessment needs to be based on a meaningful choice of exposure scenario(s) related to the research question. As a fi rst step, one needs to address whether effects of NMs are to be investigated under environmentally relevant or probable conditions, which may include processes such as agglomeration, or whether NM effects from mono-dispersed particles are of interest, which may require special steps to ensure stable NM suspension. Moreover, whether effects on cells are to be studied in the short-or long-term is important with regard to experimental design. Preparation of NM suspensions, which can be done in aqueous media different from the exposure medium, is addressed with regard to energy input, sterility (as required for algae and fi sh cell exposure) and particle purity.Specifi ed for the two model systems, algae and fi sh cell lines, availability and choice of culture media are presented and discussed with regard to impact on NM behavior. Light, temperature, and agitation, which are variables during exposure, are discussed. We further provide guidance on the characterization of the NM in the chosen aqueous exposure media regarding size, zeta potential and electrophoretic mobility. The state of NM in exposure media is decisive for their bioavailability and therefore for potential particle effects. Therefore, we present ways of deriving a mass balance and quantitative/qualitative information on the uptake and distribution of NM in cells.As NM have a high surface-to-volume ratio and possess specifi c physical-chemical properties, which make them prone to interfere with various compounds and certain types of toxicity tests, potential interferences and appropriate controls are introduced. Furthermore, different types of dose metrics, which is still a strongly debated issue in nanotoxicology, are highlighted. We also consider laboratory safety regarding NM handling and disposal.

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Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum

Cited by 43 publications

References 25 publications

Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio)

Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio)

Influence of Luminescent Nanomaterials on Plant Growth and Development

Testing Nanomaterial Toxicity in Unicellular Eukaryotic Algae and Fish Cell Lines

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