Framingham Risk Score and Coronary Artery Calcium Score: How Good they Relate

Abstract

Background and Aims: Screening patients for coronary arterial disease can be through risk stratification using the Framingham Risk Score (FRS). Direct visualization of subclinical atherosclerotic lesions through coronary artery calcium scores (CACS) can be an additional strategy. Therefore, we want to know the relationship between FRS and CACS in asymptomatic individuals. Method:A cross-sectional study involving 110 asymptomatic participants who undergoing health screening was conducted in the National Hospital, Surabaya from November 2015 until January 2016. Risk stratification was evaluated using Hard Coronary Heart Disease (10-year risk) outcomes model score and the Agatston-Janowitz's coronary calcium score.Results: A significant positive correlation was observed between CACS and FRS (Spearman's correlation coefficient r=0.51, P<0.0001). Age and systolic blood pressure were also positively correlated with CACS. Total cholesterol was the only parameter that showed a negative correlation with CACS. No difference in CACS value was shown in gender and smoking status. Conclusion:There was a strong correlation between FRS and CACS in asymptomatic individuals.