Frailty transitions and cognitive function among South Korean older adults

Nari, Fatima; Jang, Byung-Jun; Youn, Hin Moi; Jeong, Wonjeong; Jang, Sung In; Park, Sohee

doi:10.1038/s41598-021-90125-6

Cited by 22 publications

(18 citation statements)

References 36 publications

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“… 28 It indicating that frailty has become a common problem for the older adults. 29 The major reasons for this inconsistency in the present study compared with a previous study might be the geographical variations and differences in measurement tools. And the rapidly ageing population and those with chronic diseases may result in a significantly increased demand for LTC.…”

Section: Discussioncontrasting

confidence: 81%

“…However, the prevalence of frailty among older adults living in communities in the Asia-Pacific region is about 3.5%–27% 28. It indicating that frailty has become a common problem for the older adults 29. The major reasons for this inconsistency in the present study compared with a previous study might be the geographical variations and differences in measurement tools.…”

Section: Discussioncontrasting

confidence: 76%

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Relationship between frailty and long-term care needs in Chinese community-dwelling older adults: a cross-sectional study

et al. 2022

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ObjectivesOur study aimed to investigate the relationship between the severity of frailty and the long-term care (LTC) needs of older adults from Chinese communities.DesignA cross-sectional study.SettingThree Chinese community health centres. All data were collected by trained researchers through face-to-face collection.ParticipantsWe surveyed a total of 540 older residents who aged 60 or older from community in Guangzhou, China.MeasuresThe Chinese version of the Tilburg frailty indicator was used to assess the frailty status of participants. LTC needs was evaluated by Integrated Home Care Services Questionnaire. Using non-adjusted and multivariate adjusted logistic regression analysis to evaluate frailty and LTC needs, then smoothed plots, threshold effect analysis and P for trend were used to further investigate the relationship between them.ResultsThe prevalence of frailty was 45.2% among the 540 older adults enrolled (aged 70.4±8.3 years; 65.7% females). 27% had higher LTC needs, which increased to 65.1% for individuals with frailty. Logistic regression analysis showed that frailty was strongly associated with LTC needs (OR 3.06, 95% CI 2.06 to 4.55, p<0.01). In the multivariate model, after adjusting for demographic characteristics, economic situation, activities of daily living and comorbidities, frailty remained significantly associated with LTC needs (OR 2.32, 95% CI 1.39 to 3.88, p<0.01). The smoothed plots showed a nearly linear relationship between frailty and LTC needs. Threshold effect analysis showed that every point increase in frailty, the score of LTC needs increased 1.3 points. The IQR to regroup individuals with frailty. Compared with the first quartile (scores ≤2), the incidence of LTC needs increased with the frailty status (p value for trend <0.01).ConclusionThere is a linear relationship between frailty and LTC needs. With the increasing degree of frailty, the LTC needs of older adults dramatically increases.

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Section: Discussioncontrasting

confidence: 81%

Section: Discussioncontrasting

confidence: 76%

Relationship between frailty and long-term care needs in Chinese community-dwelling older adults: a cross-sectional study

et al. 2022

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“…Several studies in the literature have assessed the transitions in the frailty status, with separate times of observation and controversial results, not allowing to establish what is the best time to reassess it. 6 , 33 , 34 …”

Section: Discussionmentioning

confidence: 99%

“…Also, as we assessed subject at 3 years, there may be transitions in frailty status that we are not capturing because of the time between visits. Several studies in the literature have assessed the transitions in the frailty status, with separate times of observation and controversial results, not allowing to establish what is the best time to reassess it 6,33,34 …”

Section: Discussionmentioning

confidence: 99%

Role of sarcopenia in the frailty transitions in older adults: a population‐based cohort study

Álvarez‐Bustos

Carnicero‐Carreño

Davies

et al. 2022

J cachexia sarcopenia muscle

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Background Frailty and sarcopenia are age-associated syndromes that have been associated with the risk of several adverse events, mainly functional decline and death, that usually coexist. However, the potential role of one of them (sarcopenia) in modulating some of those adverse events associated to the other one (frailty) has not been explored. The aim of this work is to assess the role of sarcopenia within the frailty transitions and mortality in older people. Methods Data from the Toledo Study of Healthy Aging (TSHA) were used. TSHA is a cohort of community-dwelling older adults ≥65. Frailty was assessed according with the Frailty Phenotype (FP) and the Frailty Trait Scale-5 (FTS5) at baseline and at follow-up. Basal sarcopenia status was measured with the standardized Foundation for the National Institutes of Health criteria. Fisher's exact test and logistic regression model were used to determine if sarcopenia modified the transition of frailty states (median follow-up of 2.99 years) and Cox proportional hazard model was used for assessing mortality. Results There were 1538 participants (74.73 ± 5.73; 45.51% men) included. Transitions from robustness to prefrailty and frailty according to FP were more frequent in sarcopenic than in non-sarcopenic participants (32.37% vs. 15.18%, P ≤ 0.001; 5.76% vs. 1.12%; P ≤ 0.001, respectively) and from prefrailty-to-frailty (12.68% vs. 4.27%; P = 0.0026). Improvement from prefrail-to-robust and remaining robust was more frequent in non-sarcopenic participants (52.56% vs. 33.80%, P ≤ 0.001; 80.18% vs 61.15%, P ≤ 0.001, respectively). When classified by FTS5, this was also the case for the transition from non-frail-to-frail (25.91% vs. 4.47%, P ≤ 0.001) and for remaining stable as non-frail (91.25% vs. 70.98%, P ≤ 0.001). Sarcopenia was associated with an increased risk of progression from robustness-toprefrailty [odds ratio (OR) 2.34 (95% confidence interval, CI) (1.51, 3.63); P ≤ 0.001], from prefrailty-to-frailty [OR (95% CI) 2.50 (1.08, 5.79); P = 0.033] (FP), and from non-frail-to-frail [OR(95% CI) 4.73 (2.94, 7.62); Pvalue ≤ 0.001]. Sarcopenia does not seem to modify the risk of death associated with a poor frailty status (hazard ratios (HR, 95%) P > 0.05). Conclusions Transitions within frailty status, but not the risk of death associated to frailty, are modulated by the presence of sarcopenia.

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“…The Morse Fall Scale score was also included in our nomogram. This score is often regarded as a significant indicator of frailty (34)(35)(36). Additionally, this study demonstrated that surgical time might independently predict the development of SSI in patients with gynecologic cancer, with 145 min serving as the cut-off value for categorization.…”

Section: Discussionmentioning

confidence: 71%

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Frailty transitions and cognitive function among South Korean older adults

Cited by 22 publications

References 36 publications

Relationship between frailty and long-term care needs in Chinese community-dwelling older adults: a cross-sectional study

Relationship between frailty and long-term care needs in Chinese community-dwelling older adults: a cross-sectional study

Role of sarcopenia in the frailty transitions in older adults: a population‐based cohort study

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