Frailty syndrome in patients with chronic kidney disease at a dialysis Centre from Santander, Colombia

Moreno-Useche, Luis David; Urrego-Rubio, Juan; Sanabria, Miguel Oswaldo Cadena; Amaya, Reynaldo Rodriguez; Maldonado-Navas, Silvia; Ruiz-González, Carlos

doi:10.36150/2499-6564-n249

Cited by 2 publications

(1 citation statement)

References 32 publications

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“… 109 , 110 A limited number of cross-sectional studies have compared the risk of frailty progression based on maintenance dialysis modality; most of these studies conclude no difference between HD and PD, but patient selection bias confounds the interpretation of this data. 7 , 85 , 91 , 93 , 111 , 112 , 113 , 114 , 115 , 116 Frailty in PD populations remains a neglected area of research activity. 18 , 29 Studies of dialysis populations consistently report 1.4- to 3-fold increased risk of hospitalization and emergency department presentations and 2- to 5-fold hazard ratio for mortality, when adjusted for age and comorbidity.…”

Section: Prevalence Of Frailty In Nephrology Populations: An Epidemic...mentioning

confidence: 99%

Narrative Review: Clinical Implications and Assessment of Frailty in Patients With Advanced CKD

Kennard,

Glasgow,

Rainsford

et al. 2024

Kidney International Reports

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Section: Prevalence Of Frailty In Nephrology Populations: An Epidemic...mentioning

confidence: 99%

Narrative Review: Clinical Implications and Assessment of Frailty in Patients With Advanced CKD

Kennard,

Glasgow,

Rainsford

et al. 2024

Kidney International Reports

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Use of frailty assessment instruments in nephrology populations: a scoping review

et al. 2023

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Background Frailty is a clinical syndrome of accelerated aging associated with adverse outcomes. Frailty is prevalent among patients with chronic kidney disease but is infrequently assessed in clinical settings, due to lack of consensus regarding frailty definitions and diagnostic tools. This study aimed to review the practice of frailty assessment in nephrology populations and evaluate the context and timing of frailty assessment. Methods The search included published reports of frailty assessment in patients with chronic kidney disease, undergoing dialysis or in receipt of a kidney transplant, published between January 2000 and November 2021. Medline, CINAHL, Embase, PsychINFO, PubMed and Cochrane Library databases were examined. A total of 164 articles were included for review. Results We found that studies were most frequently set within developed nations. Overall, 161 studies were frailty assessments conducted as part of an observational study design, and 3 within an interventional study. Studies favoured assessment of participants with chronic kidney disease (CKD) and transplant candidates. A total of 40 different frailty metrics were used. The most frequently utilised tool was the Fried frailty phenotype. Frailty prevalence varied across populations and research settings from 2.8% among participants with CKD to 82% among patients undergoing haemodialysis. Studies of frailty in conservatively managed populations were infrequent (N = 4). We verified that frailty predicts higher rates of adverse patient outcomes. There is sufficient literature to justify future meta-analyses. Conclusions There is increasing recognition of frailty in nephrology populations and the value of assessment in informing prognostication and decision-making during transitions in care. The Fried frailty phenotype is the most frequently utilised assessment, reflecting the feasibility of incorporating objective measures of frailty and vulnerability into nephrology clinical assessment. Further research examining frailty in low and middle income countries as well as first nations people is required. Future work should focus on interventional strategies exploring frailty rehabilitation.

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Frailty syndrome in patients with chronic kidney disease at a dialysis Centre from Santander, Colombia

Cited by 2 publications

References 32 publications

Narrative Review: Clinical Implications and Assessment of Frailty in Patients With Advanced CKD

Narrative Review: Clinical Implications and Assessment of Frailty in Patients With Advanced CKD

Use of frailty assessment instruments in nephrology populations: a scoping review

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