Frail phenotype and mortality prediction: A systematic review and meta-analysis of prospective cohort studies

Chang, Shu‐Fang; Lin, Pei‐Ling

doi:10.1016/j.ijnurstu.2015.04.005

Cited by 214 publications

(199 citation statements)

References 42 publications

Supporting

Mentioning

166

Contrasting

Unclassified

Order By: Relevance

“…Sixteen articles corresponded to population-based longitudinal studies 18,[21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] . Of these studies, one was a review and meta-analysis 36 . Thirteen studies used the frailty phenotype as an operational model 18,[21][22][23][24][25][26][30][31][32][33][34]36 and four used the frailty index [27][28][29]35 .…”

Section: Resultsmentioning

confidence: 99%

“…Of these studies, one was a review and meta-analysis 36 . Thirteen studies used the frailty phenotype as an operational model 18,[21][22][23][24][25][26][30][31][32][33][34]36 and four used the frailty index [27][28][29]35 . In studies that used the frailty phenotype the samples ranged from 654 to 6724 individuals.…”

Section: Resultsmentioning

confidence: 99%

“…However, this association was more robust in men than in women. Data from the survey by Chang and Lin 36 suggest that the risk of death is higher for men, both frail and pre-frail.…”

Section: Cano Et Almentioning

confidence: 99%

See 2 more Smart Citations

Risk of death in elderly persons based on the frailty phenotype and the frailty index: a review study

Pereira

Borim

Néri

2017

Rev. bras. geriatr. gerontol.

View full text Add to dashboard Cite

Objective: to systematize studies evaluating the relationship between frailty and mortality in community-dwelling elderly persons. Method: Frailty was defined according to the frailty phenotype proposed by Fried et al. and the frailty index described by Rockwood et al. The study included epidemiologic population-based studies, cohort surveys, systematic reviews and meta-analyses published in English between 2006 and March 2016 based on the use of the terms: "frail elderly" and "mortality". Only study samples that exclusively comprised adults 65 years old or older who lived in the community were included. Studies investigating hospitalized and institutionalized elderly persons, and those examining the relationship between frailty and mortality through a disease-specific target were excluded. Results: a total of 244 studies were identified, of which 17 met the inclusion criteria. Thirteen studies used the frailty phenotype and four studies used the frailty index. Conclusion: both assessment measures found that frail elderly persons have a higher risk of death than robust elderly persons.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Risk of death in elderly persons based on the frailty phenotype and the frailty index: a review study

Pereira

Borim

Néri

2017

Rev. bras. geriatr. gerontol.

View full text Add to dashboard Cite

show abstract

“…Contudo, revendo o fenótipo da fragilidade no idoso (perda de peso, cansaço, fraqueza, baixa atividade fí-sica e dificuldade de mobilidade) 6,27,28 e os sinais e sintomas não-cognitivos de demência (alteração da marcha e do equilíbrio), 29,30 os resultados parecem refletir a coexistência do declínio da função motora e o envelhecimento e/ou a demência (declínio cognitivo). 31 A marcha era considerada como uma tarefa motora automática; todavia, a evidência emergente sugere que é uma atividade complexa que exige capacidades físicas (e.g.…”

Section: Resultsunclassified

Morbilidade em Idosos Dependentes ao Cuidado das Equipas Domiciliárias da Rede Nacional de Cuidados Continuados Integrados na Região de Lisboa e Vale do Tejo: Estudo Transversal Observacional

Broeiro-Gonçalves

2017

Acta Med Port

View full text Add to dashboard Cite

In Portugal, the National Network of Continuing Integrated Care's mission is to take care of new health and social needs. The aim of the study was to know the disease burden and disability of the elderly (75 and over) cared by the integrated continuing care teams. Material and Methods:A cross-sectional study carried out in a sample of 230 participants, from 25 teams randomly selected in the region of Lisbon and Tagus Valley. Data were collected at the patient's home trough caregiver's interviewing. The variables studied were: socio-demographic; disability determinants; degree (Barthel's scale) and duration of disability; morbidity (diagnoses, number and Charlson index). Results:The study population had: on average 84 years; low or no scholar degree level (88.7%); on average 9.5 problems per person and a Charlson index of 8.48; disability over 42 months (severe in 65.2%). The most frequent disability-determinants were: dementia, stroke and femur fracture. The most frequent diagnoses were: osteoarthritis, hypertension and dementia. Discussion: The results revealed a high disease burden (Charlson of 8.48) and disability. Although the diagnoses were those expected and comparable with the literature, their coexistence was universal, averaging 9.5 per person, affecting different organs/systems. Multimorbidity, coupled with severe disability, leads to clinical and organizational-care challenges, as well as the need for other population base studies. Conclusion:The population cared by the integrated continuing care teams is at risk: elderly, with low scholar degree level, with a high disease-burden and disability.

show abstract

“…A recent systematic review by Chang and Lin 28 , based on a sample of 35,538 elderly persons, found that the risk of mortality ratio of frail elderly persons was twice that of robust subjects over a mean follow-up period of six years (CI: 1.72 -2.36; p=0.001). The mortality risk found in our study was greater than eight of the 11 articles selected in our review.…”

Section: Discussionmentioning

confidence: 99%

Impacts of frailty on the negative health outcomes of elderly Brazilians

Barbosa¹,

Mansur

Colugnati

2017

Rev. bras. geriatr. gerontol.

View full text Add to dashboard Cite

Objective: to verify the association between frailty and the occurrence of falls, hospitalization and death among Brazilian elderly persons. Methods: a representative sample of elderly persons from the city of Juiz de Fora, Minas Gerais, Brazil, who had been evaluated with regard to frailty, socio-demographic conditions and health in 2009, were reevaluated in terms of negative health outcomes between 2014 and 2015 (n=304). Results: The results revealed a greater incidence of falls, hospitalization, and death among frail elderly persons. The frail group also had an increased risk (1.5, crude estimate) of death during the follow-up period than the robust individuals. The pre-frail elderly had a 55% (crude) and 58% (adjusted) greater risk of falls, and an 89% (crude) greater risk of death than robust individuals. Conclusion: frailty, as well as pre-frailty, can increase the risk of adverse events in the health of the elderly.

show abstract

Frail phenotype and mortality prediction: A systematic review and meta-analysis of prospective cohort studies

Cited by 214 publications

References 42 publications

Risk of death in elderly persons based on the frailty phenotype and the frailty index: a review study

Risk of death in elderly persons based on the frailty phenotype and the frailty index: a review study

Morbilidade em Idosos Dependentes ao Cuidado das Equipas Domiciliárias da Rede Nacional de Cuidados Continuados Integrados na Região de Lisboa e Vale do Tejo: Estudo Transversal Observacional

Impacts of frailty on the negative health outcomes of elderly Brazilians

Contact Info

Product

Resources

About