Fragrance material review on cinnamic acid

Letizia, C.S.; Cocchiara, J.; Lapczynski, A.; Lalko, J.; Api, A.M.

doi:10.1016/j.fct.2004.09.015

Cited by 45 publications

(40 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4 Comparison of radical scavenging activity among the substrates sorbitol, cinnamic acid, and vinyl cinnamate, as well as 6-O-cinnamoyl-sorbitol (a) and with ascorbic acid (b) by DPPH assay applications in the cosmetic field as fragrance material, thickener, and humectants [27]. In addition, there has been a report on the synergetic effect for radical scavenging activity by combining two different molecules to make an ester form [28].…”

Section: Examination Of Radical Scavenging Activity By Dpph Assaymentioning

confidence: 98%

Lipase-Catalyzed Production of 6-O-cinnamoyl-sorbitol from D-sorbitol and Cinnamic Acid Esters

Kim

Bhatia

Yoo

et al. 2015

Appl Biochem Biotechnol

View full text Add to dashboard Cite

To overcome the poor properties of solubility and stability of cinnamic acid, cinnamate derivatives with sugar alcohols were produced using the immobilized Candida antarctica lipase with vinyl cinnamate and D-sorbitol as substrate at 45 °C. Immobilized C. antarctica lipase was found to synthesize 6-O-cinnamoyl-sorbitol and confirmed by HPLC and (1)H-NMR and had a preference for vinyl cinnamate over other esters such as allyl-, ethyl-, and isobutyl cinnamate as co-substrate with D-sorbitol. Contrary to D-sorbitol, vinyl cinnamate, and cinnamic acid, the final product 6-O-cinnamoyl-sorbitol was found to have radical scavenging activity. This would be the first report on the biosynthesis of 6-O-cinnamoyl-sorbitol with immobilized enzyme from C. antarctica.

show abstract

Section: Examination Of Radical Scavenging Activity By Dpph Assaymentioning

confidence: 98%

Lipase-Catalyzed Production of 6-O-cinnamoyl-sorbitol from D-sorbitol and Cinnamic Acid Esters

Kim

Bhatia

Yoo

et al. 2015

Appl Biochem Biotechnol

View full text Add to dashboard Cite

show abstract

“…It has form as tangible crystals that are slightly soluble in water. It has a melting point of 134°C and a molecular weight of 148.16 g/mol [13]. It is a phenolic acid compound which is contained in a lot of fruits and vegetables.…”

Section: Cinnamic Acidmentioning

confidence: 99%

“…Machilus philippinense Merr. flavonol glycosides contain cinnamic compounds that have been evaluated and have activities of α-glucosidase inhibitors of type IV from Bacillus stearothermophilus with IC 50 = 6.10 µm for compounds (12) and IC 50 = 1.00 µm for compound (13) [21].…”

Section: Natural Productsmentioning

confidence: 99%

Cinnamic Acid Derivatives as α-Glucosidase Inhibitor Agents

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Many other target species can also form glucuronides, although this is generally a minor route of excretion. Several types of birds, including chickens, excrete benzoic acid as ornithuric acid (Baldwin et al, 1960;Letizia et al, 2005). In fish, benzoic acid is conjugated mainly with taurine (Schlenk et al, 2008).…”

Section: Oxidative-and Phase II Metabolismmentioning

confidence: 99%

Safety and efficacy of aryl‐substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species

Additives¹,

Rychen²,

Aquilina³

et al. 2017

EFS2

View full text Add to dashboard Cite

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 18 compounds belonging to chemical group (CG) are safe at the proposed maximum dose level of 5 mg/kg complete feed for all target species except cats, for which 1 mg/kg is safe. No safety concern would arise for the consumer from the use of these compounds up to the highest proposed level in feeds. Irritation and sensitisation hazards for skin and irritation for eye are recognised for the majority of the compounds under application. Respiratory exposure may also be hazardous. For the majority of the compounds belonging to CG 22, the maximum proposed use levels are considered safe for the environment. For a-pentylcinnamaldehyde and a-hexylcinnamaldehyde, a use level up to 0.1 mg/kg feed would not cause a risk for the terrestrial and fresh water compartments. Because all the compounds under assessment are used in food as flavourings and their function in feed is essentially the same as that in food, no further demonstration of efficacy is necessary.

show abstract

Fragrance material review on cinnamic acid

Cited by 45 publications

References 57 publications

Lipase-Catalyzed Production of 6-O-cinnamoyl-sorbitol from D-sorbitol and Cinnamic Acid Esters

Lipase-Catalyzed Production of 6-O-cinnamoyl-sorbitol from D-sorbitol and Cinnamic Acid Esters

Cinnamic Acid Derivatives as α-Glucosidase Inhibitor Agents

Safety and efficacy of aryl‐substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species

Contact Info

Product

Resources

About