Fragmentation of a Single Molten Metal Droplet Penetrating Sodium Pool I Copper Droplet and the Relationship with Copper Jet

ZHANG, Zhi-gang; Sugiyama, Ken-ichiro; Itagaki, Wataru; Nishimura, Satoshi; Kinosita, Izumi; Narabayashi, Tadashi

doi:10.3327/jnst.46.453

Cited by 2 publications

(1 citation statement)

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“…Several anilinoquinolines were established as synthetic antimalarials and have been utilized as synthons in deriving various fused heterocycles such as dibenzonaphthyridines and indoloquinoline alkaloids . Research on naphthyridine chemistry has been expanded considerably in recent years in connection with the fact that these heterocycles exceptionally own a broad spectrum of their biological activities such as anti‐arrhythmic , anti‐analgesic , therapy of disease of human including AIDS , and cancer . Particularly, some dibenzonaphthyridines, that is, quinoline dimers, act as selective 3‐phosphoinositide‐dependent kinase‐I inhibitors .…”

Section: Introductionmentioning

confidence: 99%

Effect of Substituents in the Syntheses of Phenyl‐Substituted Dibenzonaphthyridines

Manickam

Prasad

2013

Journal of Heterocyclic Chem

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A facile and elegant syntheses of linear and angular phenyl‐substituted dibenzonaphthyridines from 2,4‐dichloroquinolines through anilinoquinolines have been developed. The substituents in the 4th position of the anilinoquinoline and the temperature were found to play a vital role in the regulation of the yield towards the synthesis of the final compounds. The methyl group in the 7th position of the naphthyridin‐11‐ones was found to hinder the N‐methylation reaction sterically, consequently increasing the reaction time than other derivatives.

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