“…Several anilinoquinolines were established as synthetic antimalarials and have been utilized as synthons in deriving various fused heterocycles such as dibenzonaphthyridines and indoloquinoline alkaloids . Research on naphthyridine chemistry has been expanded considerably in recent years in connection with the fact that these heterocycles exceptionally own a broad spectrum of their biological activities such as anti‐arrhythmic , anti‐analgesic , therapy of disease of human including AIDS , and cancer . Particularly, some dibenzonaphthyridines, that is, quinoline dimers, act as selective 3‐phosphoinositide‐dependent kinase‐I inhibitors .…”