Introduction: Subtrochanteric fractures represent 10% of proximal femoral fractures. Treatment of these fractures is technically demanding and has much higher rate of complications. Theoretically, complications can be minimised by accurate reduction and internal fixation. However, there are concerns regarding effects of open reduction on fracture healing. We assessed the fracture union and complications following open reduction and internal fixation (ORIF) of irreducible subtrochanteric fractures with cables and the long proximal femoral nail (PFN). Methods: Thirty-nine patients who underwent ORIF between 2001 and 2006 were reviewed. We determined the mechanism of injury, associated injuries, fracture pattern, quality of reduction, technical difficulties and fracture union. ASA grading and other postoperative complications were recorded. Results: Thirty-nine patients (17 men and 22 women) with a mean age of 73 (range 21-93) were included. Associated injuries were noted in 12 (31%) patients. There were 17 subtrochanteric, 17 intertrochanteric with subtrochanteric extension, and 5 reverse oblique fractures. Open reduction was performed when closed reduction failed or when medial cortex was comminuted. Technical difficulties were encountered in eight patients. Twenty-seven fractures united between 3 and 12 months. Sixteen patients died within one year (within 3 months:6 patients, between 3 and 12 months:10 patients) because of complications not related to the fracture. Four patients were transferred to other hospitals for rehabilitation. All survived patients recovered expected degree of mobility. Two patients required revision (one non-union and one proximal screw migration). There was no infection. Conclusions: Treatment of subtrochanteric fractures is technically demanding. Factors including co-morbidities, pre-injury mobility, fracture configuration and bone quality need consideration. It is important to obtain a satisfactory reduction in these fractures to facilitate early mobilisation and fracture union. Treatment of irreducible subtrochanteric fractures with the long PFN and Dall Miles cables produced satisfactory fracture union.