Fractionation of Java Citronella Oil and Citronellal Purification by Batch Vacuum Fractional Distillation

Eden, Willy Tirza; Alighiri, Dante; Cahyono, Edy; Supardi, Kasmadi Imam; Wijayati, Nanik

doi:10.1088/1757-899x/349/1/012067

Cited by 20 publications

(14 citation statements)

References 10 publications

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“…Thymol, a phenolic monoterpenoid, can be isolated from various natural sources like T. vulgaris L. [ 43 ], O. dictamnus L. [ 41 ] and Arnica sachalinensis [ 47 ]. Geraniol, acyclic alcohol monoterpene, can be isolated from various sources like Rosa damascene [ 48 ], Cymbopogon winterianus [ 49 ], etc.…”

Section: Methodsmentioning

confidence: 99%

Molecules and Metabolites from Natural Products as Inhibitors of Biofilm in Candida spp. pathogens

Singla

Dubey

2019

CTMC

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Background: Biofilm is a critical virulence factor associated with the strains of Candida spp. pathogens as it confers significant resistance to the pathogen against antifungal drugs. Methods: A systematic review of the literature was undertaken by focusing on natural products, which have been reported to inhibit biofilms produced by Candida spp. The databases explored were from PubMed and Google Scholar. The abstracts and full text of the manuscripts from the literature were analyzed and included if found significant. Results: Medicinal plants from the order Lamiales, Apiales, Asterales, Myrtales, Sapindales, Acorales, Poales and Laurales were reported to inhibit the biofilms formed by Candida spp. From the microbiological sources, lactobacilli, Streptomyces chrestomyceticus and Streptococcus thermophilus B had shown the strong biofilm inhibition potential. Further, the diverse nature of the compounds from classes like terpenoids, phenylpropanoid, alkaloids, flavonoids, polyphenol, naphthoquinone and saponin was found to be significant in inhibiting the biofilm of Candida spp. Conclusion: Natural products from both plant and microbial origins have proven themselves as a goldmine for isolating the potential biofilm inhibitors with a specific or multi-locus mechanism of action. Structural and functional characterization of the bioactive molecules from active extracts should be the next line of approach along with the thorough exploration of the mechanism of action for the already identified bioactive molecules.

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Section: Methodsmentioning

confidence: 99%

Molecules and Metabolites from Natural Products as Inhibitors of Biofilm in Candida spp. pathogens

Singla

Dubey

2019

CTMC

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“…Essential Oils and Chemicals. Cymbopogon winterianus herbs were collected from Boyolali District (7°31′59″ S/110°35′44″E), Central Java, Indonesia, dried for one day, and the essential oil was subsequently obtained through a steam distillation method [10]; its active ingredients were isolated using fractional vacuum distillation and GC-MS. GC-MS analysis was carried out on an Agilent Technologies GC-MS instrument equipped with a GC 7890A gas chromatograph and an MS 5975C VL MSD mass spectrometer detector and provided with an HP-5MS capillary column. The data acquisition and data processing were performed using the MSD Chemstation E.01.01.335 (Agilent) software.…”

Section: Methodsmentioning

confidence: 99%

“…Journal of Parasitology Research albopictus, which tends to decrease over time, from 97.9% at 0 h to 71.4% at 1 h and 57.7% at 2 h [10]. Moreover, citronella oil from C. excavatus demonstrated 100% activity for 2 h against Anopheles arabiensis [12], and a mixture of C. winterianus oil and 5% vanillin provided 100% protection for 6 h against Aedes aegypti, Culex quinquefasciatus, and Anopheles dirus, compared favorably with 25% DEET [13].…”

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confidence: 97%

The Mosquito Repellent Activity of the Active Component of Air Freshener Gel from Java Citronella Oil (Cymbopogon winterianus)

Eden

Alighiri

Supardi

et al. 2020

Journal of Parasitology Research

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This study examines the active component of Cymbopogon winterianus (Java citronella) oil, as a green mosquito repellent, obtained through a steam distillation method. Java citronella oil, which contains citronellol, citronellal, and geraniol, was isolated by batch vacuum fractional distillation, and their effect was tested against the dengue fever (DF) vector, known as Aedes aegypti. Furthermore, air freshener gels were formulated with Java citronella oil, carrageenan, gum, sodium benzoate, ethylene glycol, polysorbate 20, sodium chloride, and distilled water, at varying concentrations. The results show that formula I has the best controlled release evaporation for citronellal, citronellol, and geraniol, as well as the best storage time of 16.82 days and 12.77 days for geraniol and citronellol, respectively. The most significant specific gravity (0.0136) was recorded in formula V, while gel formula I exhibited the highest level of instability at 35°C, with a syneresis value of 77.11% in t=72 h and pH 5.33. In addition, formula IV at 5°C demonstrated the highest syneresis (75.34%) in t=72 h, with pH 7.04, while a peak viscosity of 100,958 cP was recorded in formula IV. The repellent activity of each active component was measured based on the period of protection conferred against the bites of Aedes aegypti within one hour, and the results showed geraniol and citronellol, with respective activity of 78.00%±4.83 and 77.34%±3.57, as the most effective.

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“…Oleh karena itu, komponen minyak sereh wangi adalah citronellal, citronellol, dan geraniol yang manfaat paling terkenalnya sebagai mosquito repellent alami. Jadi produk hand sanitizer yang dihasilkan nanti akan mempunyai dua fungsi sekaligus (double action) yaitu selain sebagai antiseptik tangan juga berfungsi sebagai mosquito repellent alami (Choiriyah et al, 2021;Syafi 'I et al, 2020;Eden et al, 2020;Eden et al, 2018;Alighiri et al, 2017;Sastrohamidjojo, 2004).…”

Section: Pendahuluanunclassified

Application of appropriate technology for making hand sanitizer with Citronella Oil

Alighiri

Priatmoko

Kusuma

et al. 2022

ABDIMAS J. Pengabdi. Masy. Univ. Merdeka Malang

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The vision of the orphanage is to create a society that is physically and mentally prosperous through empowering underprivileged children, progressively and professionally to form a generation of Khaira Ummah. To support this, the community service team needs to equip the orphanage children with knowledge and skills that are expected to provide creative ideas in entrepreneurship through the application of appropriate technology for the production of hand sanitizer from citronella oil. The resulting hand sanitizer has two functions as a natural hand antiseptic and mosquito repellent. The stages of this community service activity had been carried out by the methods of lectures, discussions, demonstrations, and practices. After the activities were completed, assistance and evaluation of activities were carried out. Almost all participants had been a level of understanding of all community service activities ( 90%) which included knowledge, skills, perception, and motivation. The evaluation of the activities had been carried out by 95s of participants, satisfied with this community service activity. This community Service activity had been succeeded in equipping the orphanage children and supporting the vision of the orphanage of Khaira Ummah.

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Fractionation of Java Citronella Oil and Citronellal Purification by Batch Vacuum Fractional Distillation

Cited by 20 publications

References 10 publications

Molecules and Metabolites from Natural Products as Inhibitors of Biofilm in Candida spp. pathogens

Molecules and Metabolites from Natural Products as Inhibitors of Biofilm in Candida spp. pathogens

The Mosquito Repellent Activity of the Active Component of Air Freshener Gel from Java Citronella Oil (Cymbopogon winterianus)

Application of appropriate technology for making hand sanitizer with Citronella Oil

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