Fractionated Stereotactic Radiotherapy as Reirradiation for Locally Recurrent Head and Neck Cancer

Roh, Kwang-Won; Jang, Jisun; Kim, Min‐Sik; Sun, Dong‐Il; Kim, Bum Soo; Jung, So Lyung; Kang, Jin‐Hyoung; Yoo, Eun Sook; Yoon, Seung Bae; Jang, Hong-Seok; Chung, Sung-Chong; Kim, Yeon‐Sil

doi:10.1016/j.ijrobp.2008.10.013

Cited by 157 publications

(128 citation statements)

References 27 publications

(22 reference statements)

Supporting

Mentioning

120

Contrasting

Order By: Relevance

“…Stereotactic irradiation generally allows hypofractionation (doses of 2.5 Gy or more) because of the small volume of the treated tumor and the accurate delivery of irradiation. Hypofractionated stereotactic body RT has shown encouraging 2-year overall survival rates of 14% to 41% in the reirradiation setting, [27][28][29][30][31][32][33][34][35] and this approach is being increasingly investigated as a boost of prophylactic volumes after IMRT. Data for proton therapy in rare radioresistant head and neck cancer has shown high local control rates of 78% to 85% at 5 years with less than 5% severe late toxicity.…”

Section: Chemoradiation Therapymentioning

confidence: 99%

Oral complications of cancer and cancer therapy

Epstein

Thariat

Bensadoun

et al. 2012

CA A Cancer J Clinicians

395

356

View full text Add to dashboard Cite

Answer questions and earn CME/CNEOral complications resulting from cancer and cancer therapies cause acute and late toxicities that may be underreported, underrecognized, and undertreated. Recent advances in cancer treatment have led to changes in the incidence, nature, and severity of oral complications. As the number of survivors increases, it is becoming increasingly recognized that the aggressive management of oral toxicities is needed to ensure optimal long‐term oral health and general well‐being. Advances in care have had an impact on previously recognized oral complications and are leading to newly recognized adverse effects. Here, the authors briefly review advances in cancer therapy, including recent advances in surgery, oral care, radiation therapy, hematopoietic cell transplantation, and medical oncology; describe how these advances affect oral health; and discuss the frequent and/or severe oral health complications associated with cancer and cancer treatment and their effect upon long‐term health. Although some of the acute oral toxicities of cancer therapies may be reduced, they remain essentially unavoidable. The significant impact of long‐term complications requires increased awareness and recognition to promote prevention and appropriate intervention. It is therefore important for the primary oncologist to be aware of these complications so that appropriate measures can be implemented in a timely manner. Prevention and management is best provided via multidisciplinary health care teams, which must be integrated and communicate effectively in order to provide the best patient care in a coordinated manner at the appropriate time. CA Cancer J Clin 2012. © 2012 American Cancer Society.

show abstract

Section: Chemoradiation Therapymentioning

confidence: 99%

Oral complications of cancer and cancer therapy

Epstein

Thariat

Bensadoun

et al. 2012

CA A Cancer J Clinicians

395

356

View full text Add to dashboard Cite

show abstract

“…This review highlights the possible potential of BNCT in the management of patients with LRHNC, but BNCT should be compared against other emerging local re-irradiation therapeutic options for patients with LRHNC -Stereotactic Radiosurgery (Roh et al, 2009), IMRT (Lee et al, 2007) or Proton Therapy (Stuschke et al, 2013). While the availability of BNCT facilities remains limited, it has been estimated that accelerator-based BNCT facilities can be installed in hospitals at a similar cost to that of presently used for standard radiotherapy (Blue and Yanch, 2003).…”

Section: Resultsmentioning

confidence: 99%

Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer

Lim

Quah

Leech

et al. 2015

Applied Radiation and Isotopes

View full text Add to dashboard Cite

“…Roh et al 51 ). Treatment sites included the nasopharynx (8 patients), maxillary sinus (8 patients), cervical lymph nodes (8 patients), skull base (7 patients), nasal cavity (4 patients), retropharyngeal lymph nodes (3 patients), orbit (2 patients), tongue (2 patients), oropharynx (1 patient), and parotid gland (1 patient).…”

Section: Salvage Options For Recurrent Hncmentioning

confidence: 99%

“…Positron emission tomography fused with CT improves the visualization of the tumor extent. 12,[33][34][35]51 Additional information from MR imaging can also improve target volume definition, 27,48 especially in patients with nasopharyngeal cancer and skull-based tumors. 24 After defining the GTV, a clinical target volume may be defined to account for potential subclinical disease and a PTV margin to account for treatment setup.…”

Section: Defining the Target Volumementioning

confidence: 99%

Emerging applications of stereotactic radiotherapy in head and neck cancer

Truong

Grillone²,

Tschoe

et al. 2009

FOC

View full text Add to dashboard Cite

Advances in the management of locally advanced head and neck cancer (HNC) have been focused on treatment intensification, including concomitant chemoradiotherapy, biological agents, and combining surgery with chemoradiotherapy. Despite these improvements, locoregional recurrence still constitutes the main pattern of treatment failure. As improvements in radiotherapy delivery and image-guided therapy have come to fruition, the principles of stereotactic radiosurgery are now being applied to extracranial sites, leading to stereotactic body radiotherapy. This article focuses on the emerging evidence for the use of stereotactic body radiotherapy for treatment of HNC as a boost after conventional external-beam radiotherapy, and also as reirradiation in recurrent or second primary HNC.

show abstract

Fractionated Stereotactic Radiotherapy as Reirradiation for Locally Recurrent Head and Neck Cancer

Cited by 157 publications

References 27 publications

Oral complications of cancer and cancer therapy

Oral complications of cancer and cancer therapy

Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer

Emerging applications of stereotactic radiotherapy in head and neck cancer

Contact Info

Product

Resources

About