Fractionated Stereotactic Conformal Radiotherapy for Optic Nerve Sheath Meningiomas

Soldà, Francesca; Wharram, B.; Gunapala, R.; Brada, Michael

doi:10.1016/j.clon.2012.03.015

Cited by 31 publications

(27 citation statements)

References 48 publications

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“…Recent reports have suggested the safety of both radiotherapy and radiosurgery for optic nerve sheath meningiomas. [13][14][15][35][36][37][38][39] However, these experiences report mainly treatments involving intra-orbital structures. For this reason, they are unable to define the real risk of RION whenever the optic chiasm is directly involved.…”

Section: Discussionmentioning

confidence: 97%

Multisession Radiosurgery for Sellar and Parasellar Benign Meningiomas

et al. 2016

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Section: Discussionmentioning

confidence: 97%

Multisession Radiosurgery for Sellar and Parasellar Benign Meningiomas

et al. 2016

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“… 84 If identified, radiation retinopathy can be treated with intravitreal antivascular endothelial growth factor antibodies. 74 , 85 , 86 …”

Section: Treatment Optionsmentioning

confidence: 99%

Optic nerve sheath meningiomas: prevalence, impact, and management strategies

Parker

Ovens

Fraser

et al. 2018

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Optic nerve sheath meningiomas are rare benign neoplasms of the meninges surrounding the optic nerve. They are a significant cause of morbidity. While the mortality rate is practically zero, these tumors can blind or disfigure patients. Given that the clinical course can be variable, and treatment has the capacity to cause morbidity itself, the management of these patients can be difficult. We review the literature to discuss the prevalence of optic nerve sheath meningiomas, the association with neurofibromatosis type 2, natural history, and management options and strategies.

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“…FRT is the first-line treatment of choice for optic nerve sheath meningioma (ONSM) because of high risk of blindness after surgery, even on biopsy [29]. ONSM either remains stable or reduces in size after FRT in 95-100% of cases (Table 3), and visual symptoms are stable or improve in 80-90% [30][31][32][33][34][35][36][37][38][39][40].…”

Section: Indications and Outcomesmentioning

confidence: 98%