“…During this time, energy in the form of radiation is delivered to the area of the vaginal opening and the vaginal canal. First placebo-controlled RCT reports no statistically significant differences in any parameter (vaginal histopathology and cytology, self-reported symptom severity by visual analogue scale of most bothersome symptom, impact on livelihood, quality of life and sexual function) between placebo and intervention groups using fractionated CO 2 laser for postmenopausal vaginal atrophy symptoms [ 8 ].…”