2002
DOI: 10.1016/s1278-3218(02)00179-8
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Fractionated half-body irradiation (HBI) for the rapid palliation of widespread, symptomatic, metastatic bone disease: a randomized Phase III trial of the International Atomic Energy Agency (IAEA)

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Cited by 17 publications
(34 citation statements)
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“…When larger or multiple fields of irradiation are necessary (such as for multiple metastases in the vertebra and in the pelvis), bone marrow suppression increases and is visualized by a shift from active red to fibrous yellow bone marrow on magnetic resonance imaging in irradiated bones. Hence, widefield external irradiation in patients with disseminated skeletal metastases is not frequently used and is also associated with significant acute gastrointestinal toxicity (16).…”
Section: Radiotherapymentioning
confidence: 99%
“…When larger or multiple fields of irradiation are necessary (such as for multiple metastases in the vertebra and in the pelvis), bone marrow suppression increases and is visualized by a shift from active red to fibrous yellow bone marrow on magnetic resonance imaging in irradiated bones. Hence, widefield external irradiation in patients with disseminated skeletal metastases is not frequently used and is also associated with significant acute gastrointestinal toxicity (16).…”
Section: Radiotherapymentioning
confidence: 99%
“…QoL indices were evaluated using cancer linear analog scales, for well-being (CLAS1), fatigue (CLAS2) and ability to perform daily activities (CLAS3), respectively (23). The visual analog scale (VAS) for pain (24), the pain score (pain evaluation obtained by multiplying severity x frequency) and the drugs score (analgesic assumption evaluation obtained by multiplying severity x frequency) were used to record and monitor pain (25).…”
Section: Methodsmentioning
confidence: 99%
“…Patients scored their perceptions of these symptoms by placing a mark on a 100-mm line to indicate magnitude of the symptom (21). The visual analog scale (VAS) for pain, the Pain score (pain evaluation obtained by multiplying severity x frequency) and the Drugs score (analgesic assumption evaluation obtained by multiplying severity x frequency) were used to record and monitor pain (22). The weight and ECOG score of patients before and after (3-4 weeks) ESRT were recorded by nursing staff.…”
Section: Methodsmentioning
confidence: 99%