Fractional Photothermolysis in Acne Scars

Beer, Gillian; Zito, Patrick M.; Gonzalez, Adrianna; Beer, Kenneth

doi:10.1201/9781315179889-10

Cited by 1 publication

(4 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16 Laser resurfacing involves monochromatic light delivery into the scars, and resultant heat initiates collagen injury and neocollagenesis. 17 Fractional resurfacing (FR) leads to formation of MTZ (microthermal zones) by ablation of epidermal and dermal tissue without injuring the adjacent skin, which leads to rapid wound healing in ablated area. 17 Delivery of laser beam causes ablation where most superficial layer undergoes vaporization and creates a zone of vaporization.…”

Section: Photographic Assessmentmentioning

confidence: 99%

“…17 Fractional resurfacing (FR) leads to formation of MTZ (microthermal zones) by ablation of epidermal and dermal tissue without injuring the adjacent skin, which leads to rapid wound healing in ablated area. 17 Delivery of laser beam causes ablation where most superficial layer undergoes vaporization and creates a zone of vaporization. High heat below this zone causes tissue necrosis, creating a zone of irreversible damage.…”

Section: Photographic Assessmentmentioning

confidence: 99%

“…Due to fractional ablation of epidermis and dermis, the adjoining non-ablated skin and appendages assist re-epithelialization. 17 Platelet-rich plasma (PRP) is an autologous blood plasma containing 4-7 times the baseline concentration of platelets and is pre-packed with growth factors. 19 Autologous growth factors and secretory proteins, chemokines, and cytokines released on platelet activation facilitate wound repair and rejuvenation in cosmetic dermatology, they act by stimulation of dermal fibroblast proliferation and increase type I collagen synthesis.…”

Section: Photographic Assessmentmentioning

confidence: 99%

“…19 Autologous growth factors and secretory proteins, chemokines, and cytokines released on platelet activation facilitate wound repair and rejuvenation in cosmetic dermatology, they act by stimulation of dermal fibroblast proliferation and increase type I collagen synthesis. 17 GFs and cytokines are released from platelets during clot formation at wound site. 20 Different growth factors and their biological roles are summarized in (Table 5).…”

Section: Photographic Assessmentmentioning

confidence: 99%

See 3 more Smart Citations

Laser for post acne scars with or without growth factors: a comparative clinical trial

2020

View full text Add to dashboard Cite

Background: Treatment of acne scars presents a considerable challenge to dermatologists. But with advent of fractional CO2 (FCO2) laser and platelet-rich plasma (PRP), new avenues can be explored. PRP provides various growth factors, so that the healing of laser-damaged skin is accelerated. The aim of this study was to assess the efficacy and safety of FCO2 laser alone and in combination with PRP in patients with post-acne scars.Methods: Eighty patients with acne scars were counseled and randomly assigned into two groups of 40 each. Group A was treated with FCO2 laser alone, while Group B was treated with FCO2 laser and PRP for 6 months. Primary objective was assessment of efficacy of both treatment modalities. Secondary objective was evaluation of safety of treatments.Results: At the end of 6 months, group A showed about 18% reduction, while group B showed about 33% reduction in acne scars on objective assessment. Patient satisfaction as assessed by subjective assessment was greater in group B than in group A. Duration of erythema, edema and crusting was lesser in group B compared to group A.Conclusions: Combination of FCO2 and PRP was found to be more efficacious as compared to FCO2 laser alone. Combining the treatment modalities can provide a new strategy for treating the post-acne scars.

show abstract

Section: Photographic Assessmentmentioning

confidence: 99%

Section: Photographic Assessmentmentioning

confidence: 99%