Fractional ablative carbon dioxide laser resurfacing for skin rejuvenation and acne scars in Asians

Chan, Nicola P Y; Ho, Stephanie G Y; Yeung, Chi K; Shek, Samantha Y N; Chan, Ho Lung Henry

doi:10.1002/lsm.20974

Cited by 79 publications

(107 citation statements)

References 36 publications

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“…In study by Simin et al, 13 85% patient showed 30 -70% reduction in acne scars which is comparable with our study in which 96.7% patients showed 25 -80% reduction in acne scars. In study by Chan et al, 14 86% patient showed good and fair efficacy. In study by Manuskiatti et al, 15 85% patients showed more than 25% reduction in acne scars.…”

Section: 12mentioning

confidence: 91%

Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

Saeed

Rani²,

Aslam³

2017

Annals KEMU

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Acne having a prevalence of > 90% in adolescents persisting in adulthood, causes inflammation and scaring. Acne scars cause severe social, psychological and cosmetic problems. There are many remedies available for acne scars with variable results. CO2-AFR laser is a new modality with more effectiveness and low side effect profile. Objective: To determine the effectiveness and safety of CO2-AFR device in the treatment of moderate to severe atrophic acne scars.

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Section: 12mentioning

confidence: 91%

Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

Saeed

Rani²,

Aslam³

2017

Annals KEMU

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“…PIH rates in darker skin types III, IV, and V have been as high as 50%, 55.5%, and 92%, respectively, after fractional CO2 treatment. 39,42,43 PIH has been associated with higher-density settings. [44][45][46] Nonablative fractional lasers NAFLs utilize a wavelength of light in the midinfrared spectrum that penetrates into the midreticular dermis, inducing new collagen formation and tissue remodeling.…”

Section: Safety and Adverse Eventsmentioning

confidence: 99%

“…Side effects did not vary depending on underlying condition or skin type, except for PIH, which occurred with an increased frequency in patients with darker skin types. 73 Similar to AFLs, lower densities and fewer treatment passes have been associated with a lower risk for hyperpigmentation at the expense of more treatment sessions, 43 whereas higher densities result in more side effects without improved results. 40 Pre-and posttreatment with hydroquinone 4% may help decrease the incidence of PIH, even in darker patients.…”

Section: Safety and Adverse Eventsmentioning

confidence: 99%

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

2017

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I n recent decades, there has been a revolution in energy-based treatment options for skin scarring, rejuvenation, and tightening. One of the most promising developments has been the introduction of fractional photothermolysis, developed by Anderson and Manstein in 2004. Fractionated systems deliver laser energy in a grid-like pattern, creating microscopic columns of ablative and/or coagulative damage termed microthermal zones (MTZs), which stimulate collagen remodeling.1 The incorporation of fractional photothermolysis into energy-based devices has allowed less destruction to surrounding tissue, leading to desired results with the minimization of unwanted side effects, leading to both ablative and nonablative laser devices becoming desirable treatment options for cutaneous scarring and rejuvenation. Given their impressive results, newer fractional laser treatment options, including picosecond lasers, quality-switched (QS) lasers, and combined ablative and nonablative lasers, are being investigated for the treatment of these common skin conditions.The following review addresses the current and emerging topics on fractional laser treatment of skin scarring and rejuvenation based on the device type, including ablative, nonablative, QS, picosecond, and hybrid fractional lasers (HFLs). Additionally, newer energy-based fractional devices, such as radiofrequency (RF) with and without microneedling and the use of fractionated technology for drug delivery, are discussed in the context of these common skin conditions. Fractionated lasersTreatment options for cutaneous scars and skin rejuvenation have evolved significantly since the rise in popularity of ablative lasers in the 1990s. Newer treatment options, including ablative fractional lasers (AFL) and nonablative fractional lasers (NAFL), have garnered favor, given the milder side effect profile in comparison with traditional fully ablative lasers. Ablative fractional lasersAcne scarring AFLs were developed in an attempt to achieve the efficacy of traditional ablative lasers with the milder side effect profile of fractional technology. Although a single treatment produces less dramatic, albeit noticeable, results than traditional fully ablative lasers can, multiple treatments result in greater clinical improvement.2 Currently, there are 3 types of AFLs available for scar treatment: the 10600-nm carbon dioxide (CO2), the 2940-nm erbium:yttrium aluminum garnet (Er:YAG), and the 2740-nm yttrium scandium gallium garnet (YSGG) lasers. AFL is associated with the increased risk of both protracted erythema and postinflammatory hyperpigmentation (PIH) in darker skin types, which has led many clinicians to prefer a longer series of NAFL treatments over AFL treatments to achieve similar results with a lower risk of side effects.Multiple studies support the efficacy of the fractional CO2 laser in acne scars. The overwhelming majority of these studies investigate the utility of these lasers in atrophic facial scars. While NAFLs typically require multiple sessions to achieve modest ...

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“…Up to 1 mm in depth can be achieved with fractionated CO 2 , thus inducing greater collagen production and dermal remodeling than nonablative fractionated photothermolysis [42]. Persistent collagen remodeling with wound healing response occurs up to 3 months after in vivo fractional CO 2 ablative laser [43].…”

Section: Atrophic Acne Scarsmentioning

confidence: 99%

Scar Treatment with Lasers: A Review and Update

Harithy

Pon

2012

Curr Derm Rep

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Fractional ablative carbon dioxide laser resurfacing for skin rejuvenation and acne scars in Asians

Cited by 79 publications

References 36 publications

Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

Scar Treatment with Lasers: A Review and Update

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