Fr503 FEAR OF COVID-19, ALONG WITH STRESS, ANXIETY, AND DEPRESSION, IS ASSOCIATED WITH BIOLOGIC USAGE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Shah, Rishabh; Dua, Anoushka; Naliboff, Bruce D.; Tripathi, Priyam; Mocharla, Robert; Lin, Lisa; Sauk, Jenny; Limketkai, Berkeley N.

doi:10.1016/s0016-5085(21)01524-9

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“…Additionally, the number of IBD patients in South Korea has increased in the prior decade, and psychological issues are important among such patients [ 8 ]. Compared with non-IBD patients, IBD patients have a higher level of fear concerning the potential for contracting COVID-19 [ 9 , 10 ]. According to a survey conducted by the Korean Association for the Study of intestinal diseases (KASID) in 2021, more than half of IBD patients in South Korea showed a high level of fear of COVID-19 [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Psychological Effects and Medication Adherence among Korean Patients with Inflammatory Bowel Disease during the Coronavirus Disease 2019 Pandemic: A Single-Center Survey

Ryu

Jung

Lee

et al. 2022

JCM

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Background and Aim. This study evaluated the impact of coronavirus disease 2019 (COVID-19) on the mental health of inflammatory bowel disease (IBD) patients. We quantified anxiety, depression, and medication adherence among IBD patients through a single-center survey in South Korea during the COVID-19 pandemic. Methods. An electronic survey was made available to patients at the IBD clinic in Daejeon St. Mary’s hospital from July 2021 to September 2021. The validated Hospital Anxiety and Depression Scale (HADS) was used to assess depression and anxiety. The Korean version of the Medication Adherence Rating Scale (KMARS) questionnaire was used to assess medication adherence. Results. In total, 407 patients (56.5%; ulcerative colitis, 43.5%; Crohn’s disease) participated in the survey. Among the respondents, 14.5% showed significant anxiety and 26.3% showed significant depression. Female sex, presence of mental disease, unvaccinated status, and the presence of Crohn’s disease were associated with greater risks of anxiety and depression. Among medications, immunomodulators were associated with a greater risk of anxiety. In terms of KMARS, patients reported favorable medication adherence despite the psychological burden of the pandemic. The KMARS score was 7.3 ± 1.5 (mean ± SD) of 10.0 points. High anxiety and depression were associated with a slight decrease in medication adherence. Conclusions. COVID-19 has increased anxiety and depression among IBD patients, whose medication adherence has nevertheless remained good. Furthermore, anxiety and depression were found to have a negative correlation with adherence. Our results provide insights concerning psychological response and medication adherence among IBD patients in South Korea during the COVID-19 pandemic.

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Section: Introductionmentioning

confidence: 99%