2012
DOI: 10.1109/tps.2012.2188908
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FPGA-Controlled All-Solid-State Nanosecond Pulse Generator for Biological Applications

Abstract: In vivo studies of tumor-cell apoptosis induced by nanosecond pulsed electric field require high-voltage nanosecond pulses delivered to the biological tissues. In this paper, a newly developed all-solid-state nanosecond pulse generator based on the Marx generator concept is proposed for this application. The generator comprises four parts: a dc charging power, a solid-state Marx circuit using metal-oxide-semiconductor field-effect transistors, a control circuit using a field-programmable gate array, and the lo… Show more

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Cited by 45 publications
(17 citation statements)
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“…Although the sinusoidal power supply has the advantages of simple structure and lower prices [18][19][20][21][22], existing research demonstrates that the use of all solid-state pulsed power supplies (i.e., unipolar or bipolar Marx modulators) is more efficient. Therefore, there has been much research and many applications with all solid-state Marx modulators for DBDs [23][24][25][26][27].…”
Section: Introductionmentioning
confidence: 99%
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“…Although the sinusoidal power supply has the advantages of simple structure and lower prices [18][19][20][21][22], existing research demonstrates that the use of all solid-state pulsed power supplies (i.e., unipolar or bipolar Marx modulators) is more efficient. Therefore, there has been much research and many applications with all solid-state Marx modulators for DBDs [23][24][25][26][27].…”
Section: Introductionmentioning
confidence: 99%
“…Efficiency is the most crucial product feature in scientific applications and industry, especially for DBDs. At present, the study of the efficiency of an all solid-state Marx modulator is primarily focused on resistive load [25][26][27]. A generalized solid-state Marx modulator efficiency was calculated from the ratio between the input power (from the measured average voltage and current values) and the output power delivered to the load (from the measured current and voltage waveforms) using resistive loads, and its was 85.5% [25].…”
Section: Introductionmentioning
confidence: 99%
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“…We analyzed the performance of the proposed gripper formations with respect to their maximum transport speeds and the laser intensity experienced by the cell that depends on the laser power used [17]. Yao et al proposed a newly developed all-solid-state nanosecond pulse generator based on the Marx generator concept for this application [18]. Chen et al presented a novel approach for the automated transportation of multiple cells by using robotically controlled holographic optical tweezers [19].…”
Section: Introductionmentioning
confidence: 99%
“… With the reduced number of IGBTs than in SMPG1, SMPG2 [23] (shown in Fig. 6b) can provide unipolar pulses by simultaneous turn ON of all switches for the required pulse time.…”
mentioning
confidence: 99%