Abstract:Appropriate patterning of the retina during embryonic development is assumed to underlie the establishment of spatially localised specialisations that mediate the perception of specific visual features. For instance, in zebrafish, an area involved in high acuity vision (HAA) is thought to be present in the ventro-temporal retina. Here we show that the interplay of the transcription factor Rx3 with Fibroblast Growth Factor and Hedgehog signals, initiates and restricts foxd1 expression to the prospective tempora… Show more
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