Fox Fordyce disease: a side effect of laser therapy

Zargari, Omid; Azimi, Seyyede Zeinab

doi:10.1080/14764172.2020.1774062

Cited by 3 publications

(5 citation statements)

References 5 publications

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“…1 A few cases of laser or light hair removal-induced FFD were reported during the past decade. [1][2][3][4][5][6][7][8][9][10] The clinical and histopathologic features of 13 laser or light hair removal-induced FFD are summarized in Tables 1 and 2. All cases are women, which may reflect the more prevalent laser hair removal in women.…”

Section: Discussionmentioning

confidence: 99%

“…Fox–Fordyce disease may occur at limited sites undergone laser hair removal or at all sites 7,10 . The variable density of apocrine glands and different skin phototypes are propounded as possible causes of sparing of laser hair removal FFD in some laser‐treated areas and patients 10 …”

Section: Discussionmentioning

confidence: 99%

“…7,10 The variable density of apocrine glands and different skin phototypes are propounded as possible causes of sparing of laser hair removal FFD in some laser-treated areas and patients. 10 Variable histopathological features of FFD are described in FFD lesions, including hyperkeratosis, dilation of the follicular infundibulum, follicular plugging, acanthosis, spongiosis, dyskeratotic cells in the infundibulum, perifollicular lymphohistiocytic infiltrate with mast cells, apocrine secretary unit dilation, perifollicular fibrosis, and perifollicular xanthomatosis. 1,3 While perifollicular xanthomatosis is generally reported in FFD cases and considered the hallmark of classic FFD, some laser hair removal cases lack foam cells.…”

Section: Discussionmentioning

confidence: 99%

“…A few cases of laser or light hair removal‐induced FFD were reported during the past decade 1–10 . The clinical and histopathologic features of 13 laser or light hair removal‐induced FFD are summarized in Tables 1 and 2.…”

Section: Discussionmentioning

confidence: 99%

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Hair removal laser‐induced Fox–Fordyce disease emerging on the axillary and pubic areas: Report of a case and review of literature

Sepaskhah,

Hamedpour,

Sari Aslani

2024

Clinical Case Reports

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Key Clinical MessageFox–Fordyce disease is a recognized adverse effect of depilating lasers. It should be considered among the differential diagnoses of the pruritic perifollicular papules that occur at the hair removal laser treatment site, including Alex/Diode laser.AbstractFox–Fordyce disease (FFD) is an uncommon skin disorder affecting the apocrine sweat glands and presents as pruritic skin‐colored papules, mainly on the axillary and pubic areas. Some predisposing factors are proposed, including hormonal changes. A few cases of FFD have been reported after hair removal by light‐ and laser‐assisted devices. Herein, we report FFD in some areas (axillary and pubic areas) treated with Alex/Diode hair removal laser.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Hair removal laser‐induced Fox–Fordyce disease emerging on the axillary and pubic areas: Report of a case and review of literature

Sepaskhah,

Hamedpour,

Sari Aslani

2024

Clinical Case Reports

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“…Laser operators should report novel adverse events in the literature and share them with the medical community. 107 -139…”

Section: Discussionmentioning

confidence: 99%

Adverse Events of Light-Assisted Hair Removal: An Updated Review

et al. 2023

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Background With light-assisted hair removal becoming widely used, reports of adverse effects are increasing. Objective To review all the reported optical incidents and cutaneous complications of laser or intense pulse light-assisted hair removal. Methods A PubMed database systematic search was performed to identify studies reporting such adverse events before July 2022 using the Mesh terms “adverse effects” AND “hair removal” AND (“laser” OR “intense pulse light”). Results Altogether, 358 references were identified. After excluding duplicates, unrelated articles, guidelines, and conference abstracts, then adding references from studies bibliography, 104 publications were included. Ocular incidents consisted of anterior uveitis, iritis and iris atrophy, pupillary distortion, posterior synechiae, anterior chamber pigment, and cataracts in the anterior subcapsular region. Cutaneous complications consisted of pain, burns, folliculitis, leukotrichia, paradoxical hypertrichosis, pigmentary changes, changes in nevi, pili bigemini, herpes infection, hyperhidrosis, bromhidrosis, Fox-Fordyce disease, and frostbite from the cooling system. They were mostly correlated to skin type and body area as well as to light device and set parameters. Intense pulse light devices were found to be less painful than alexandrite laser, yet more painful than diode laser; Nd:YAG laser had the highest pain score. Conclusion Optical incidents can be systematically avoided. Cutaneous complications are usually related to professional errors and patient characteristics. Better knowledge of laser physics and adequate training of laser operators are key recommendations to avoid undesirable side effects. Safety recommendations help prevent most of the reported complications.

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