Foveal Pit Morphology Evaluation during Optical Biometry Measurements using a Full-Eye-Length Swept-Source OCT Scan Biometer Prototype

Bertelmann, Thomas; Blum, Marcus; Kunert, Kathleen S.; Haigis, W.; Messerschmidt-Roth, Anke; Peter, Monika; Buehren, Tobias F.; Sekundo, Walter

doi:10.5301/ejo.5000630

Cited by 12 publications

(10 citation statements)

References 27 publications

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“…Further analysis in Bertelmann et al . 8 study revealed a diagnostic advantage of the IOLMaster 700 in the detection of macular alterations during the preoperative biometrical measurements, especially for ERM, FTMH as well as IRF. Although data on different macular pathologies were reported, none sensitivity and specificity analysis for each alteration have been assessed in that study.…”

Section: Discussionmentioning

confidence: 88%

“…Bertelmann et al . 8 for the first time evaluated the foveal pit morphology during optical biometer measurements using the full-eye-length SS-OCT scan biometer. In this prospective study, 146 eyes were classified into two groups: phakic, non-vitrectomized eyes scheduled for cataract surgery and pseudophakic non-vitrectomized eyes with acrylic lenses.…”

Section: Discussionmentioning

confidence: 99%

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Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

Tognetto

Pastore

Giacinto

et al. 2019

Sci Rep

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The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underwent a biometrical examination with IOLMaster 700 SS-OCT technology (Carl Zeiss) and conventional Spectral-Domain OCT (SD-OCT) (Spectralis OCT, Heidelberg) device analysis on the same day. Seven examiners graded the scans individually in a full-masked mode. Twenty-five eyes were excluded for media opacities. Among the 1,089 included eyes, statistical analysis revealed a mean Kendall’s Coefficient of 0.83 (range 0.76–0.89). A logistic regression model demonstrated a highly significant correlation (p < 0.001) between the coefficient of concordance and SD-OCT imaging. Intraobserver reproducibility was 0.89 (range 0.86–0.91). Optical biometer SS-OCT scans showed a mean sensitivity of 0.81 and a mean specificity of 0.84. The positive and negative predictive value detected was 0.78 and 0.86, respectively. In order to predict the risk of reduced visual recovery, especially in cases of retinal pathology, optical biometer with SS-OCT scan has proven to be a useful modality for detecting macular structural abnormalities in patients undergoing cataract surgery. Conventional SD-OCT remains mandatory to confirm the presumed diagnosis.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

Tognetto

Pastore

Giacinto

et al. 2019

Sci Rep

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“…It was reported that SS-OCT is able to better identify the choroidoscleral junction as compared to conventional spectral-domain OCT (SD-OCT) (8). Furthermore, when compared with SD-OCT, SS-OCT was shown to have better repeatability and accuracy of measurements (9).…”

Section: Introductionmentioning

confidence: 99%

Retinal and Choroidal Thicknesses Measured with Swept-Source Optical Coherence Tomography after Surgery for Idiopathic Macular Hole

Bardak

Günay

Bardak

et al. 2016

European Journal of Ophthalmology

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“…Bertelmann et al ( 15 ) first evaluated the repeatability and precision of the central retinal thickness measured by SS-OCT compared to SD-OCT, which revealed the feasibility of optical biometer with SS-OCT as a macular disease screening method. Two studies had evaluated the value of using SS-OCT for the detection of macular disease, and one study further demonstrated that compared to fundus biomicroscopy, SS-OCT significantly improved the detection of macular disease in cataract patients ( 10 ).…”

Section: Discussionmentioning

confidence: 99%

Impact of lens opacity and axial length on concomitant screening of maculopathy by swept-source optical coherence tomography-based optical biometer

Qin¹,

Ye²,

Liu³

et al. 2022

Ann Transl Med

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Background Preoperative evaluation of macular disorders is crucial to predict postoperative visual outcomes among patients with cataract. The swept-source optical coherence tomography (SS-OCT) based optical biometer was proved to be useful in screening macular pathology, while the impact of lens opacities and axial lengths on macular disease screening using SS-OCT based optical biometer remained unknown. This study aimed to evaluate the influence of lens opacities and axial lengths on foveal image quality detected by SS-OCT-based optical biometer, as well as sensitivity and specificity for the detection of macular diseases. Methods This was a diagnostic accuracy study that retrospectively included patients who underwent preoperative cataract examinations at our hospital between November 2020 and June 2021. All patients underwent SS-OCT based optical biometer and spectral-domain OCT (SD-OCT). The SD-OCT was the golden standard for diagnosing macular diseases. Sensitivity, specificity, and receiver operating characteristic (ROC) were calculated to evaluate the value of foveal SS-OCT scans for the detection of macular disease. Results Of the 224 eyes enrolled in the study, 82 eyes were diagnosed with macular disease by SD-OCT. The foveal image was almost indistinguishable due to poor quality when the mean grayscale of the image was less than 40. The posterior subcapsular opacity score and the axial length were significantly correlated with the gray density of the foveal image (r=−0.70, P<0.0001 and r=−0.40, P<0.0001). After excluding cases with indistinguishable foveal images (subcapsular opacities score ≥3.5, axial length ≥28.9 mm), the SS-OCT yielded 68% (95% confidence interval, 0.54–0.79) sensitivity and 87% (95% confidence interval, 0.78–0.92) specificity in 136 eyes. Conclusions Routine SS-OCT based biometric measurement for the evaluation of macular pathology simultaneously prior to cataract surgery is suggested except for patients with advanced cataract (posterior subcapsular opacities score ≥3.5) and long axial length (≥28.9 mm).

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Foveal Pit Morphology Evaluation during Optical Biometry Measurements using a Full-Eye-Length Swept-Source OCT Scan Biometer Prototype

Cited by 12 publications

References 27 publications

Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

Retinal and Choroidal Thicknesses Measured with Swept-Source Optical Coherence Tomography after Surgery for Idiopathic Macular Hole

Impact of lens opacity and axial length on concomitant screening of maculopathy by swept-source optical coherence tomography-based optical biometer

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