Foveal Densitometry in Central Serous Choroidopathy

Meel, Gerard J. van; Smith, Vivianne C.; Pokorny, Joel; Norren, Dirk van

doi:10.1016/0002-9394(84)90329-5

Cited by 25 publications

(7 citation statements)

References 5 publications

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“…Patients with central serous chorioretino pathy reportedly have moderately decreased visual acuity [1,[8][9][10][11][12][13]. The visual acuities of our patients were also moderately diminished at the initial visit, but they improved after re covery.…”

Section: Discussionmentioning

confidence: 68%

“…Although a 7-year-old girl, a 9-year-old boy and a 68-year-old man with central serous chorioretinopathy had been previously reported [7,8]. most described pa tients with the disease have been young to middle-aged [1,6,[9][10][11][12][13]. Gass [1] has reported that idiopathic central serous chorioretino pathy typically affects young and middle-aged adults between 20 and 45 years of age.…”

Section: Discussionmentioning

confidence: 99%

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Fluorescein-Angiographic Patterns in Patients with Central Serous Chorioretinopathy at the Initial Visit

Yamada

Hayasaka

Setogawa³

1992

Ophthalmologica

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We reviewed the clinical records, color photographs and fluorescein angiograms of 106 eyes of 53 patients (44 men and 9 women) with central serous chorioretinopathy who had been followed up for 1 year or more. Their ages ranged from 20 to 59 years. One eye in each patient was involved at the initial visit. According to fluorescein-angiographic findings, the lesions were divided into smokestack pattern (13 eyes), ink blot appearance (33 eyes) and minimally enlarging spot (7 eyes). Most patients complained of central scotoma, and most patients had moderately decreased visual acuities at the initial visit, which improved after recovery. In particular, all 7 eyes with a minimally enlarging spot had a visual acuity of 0.8 or more at the initial visit; of these 6 eyes had 1.0 or more several weeks later. On fluorescein angiography, 49 eyes demonstrated 1 leaking spot and 4 eyes showed 2 spots. Of 57 leaking spots, 10 were observed in the foveola, 31 were noted in the fovea and 16 were found in the para- or perifovea. Of 13 smokestack patterns, 5 were found in the inferonasal area. The ink blot appearance and minimally enlarging spots were frequently found in the superonasal and superotemporal areas.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 99%

Fluorescein-Angiographic Patterns in Patients with Central Serous Chorioretinopathy at the Initial Visit

Yamada

Hayasaka

Setogawa³

1992

Ophthalmologica

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“…3 4 Since CSR is characterized by a separation of the sensory retina from the retinal pigment epithelium, one of the best ways to evaluate the status of a patient is to measure the concentration of photopigment near the elevation as well as the kinetics of photopigment bleaching and regeneration. 5 6 Van Meel et al 5 reported that cone photopigment kinetics, as measured by retinal densitometry, are slowed during periods of active leakage. Measurements with an imaging densitometer 7 indicate that rod photopigment concentration is abnormally low, even when the elevated portion of the retina has flattened, indicating continued abnormalities in the retinal pigment epithelium/photoreceptor complex.…”

Section: Introductionmentioning

confidence: 99%

Foveal cone photopigment bleaching in central serous retinopathy

1988

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Color-matching techniques were used to follow the course of central serous retinopathy in thirteen patients. During periods of neurosensory detachment?, cone optical densities were low. In some patients optical densities remained low following clinical resolution of the disease. In addition, abnormalities of bleaching were observed for one patient in one eye that appeared clinically unaffected during a period of detachment of the fellow eye. Analysis of the data indicates that for longitudinal measurements of optical density, standard Nagel anomaloscope matches can provide an accurate estimate of changes in foveal optical density, although they cannot provide a measure of the absolute optical density.

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“…These results suggest that the bleaching and recovery processes are functioning normally in the area without retinal detachment and choroidal abnormality. Slow regeneration of visual pigment in the detached area has been reported using conventional PSRT1and foveal densitometry 24. Densitometry revealed a reduced two way density and a prolonged time constant, indicating a reduction and abnormal kinetics of the visual pigment.…”

Section: Discussionmentioning

confidence: 83%

Extrafoveal photostress recovery test in glaucoma and idiopathic central serous chorioretinopathy

Horiguchi

Ito

Miyake

1998

British Journal of Ophthalmology

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Background/aims-A photostress recovery test was designed to diVerentiate macular diseases from optic nerve disorders, but recently an abnormal recovery time was reported in glaucoma. The purpose of this study was to search for the diVerence in abnormality of the photostress recovery test between glaucoma and idiopathic central serous chorioretinopathy (ICSC). Methods-This study involved 21 normal subjects, 14 patients, with ICSC and 10 patients with primary open angle glaucoma (POAG). A scanning laser ophthalmoscope (SLO) was used with microperimetry for bleaching the test point and measuring the recovery of sensitivity. Photostress recovery time (SLO-PSRT) could be measured at extrafoveal points outside and inside the affected area. The initial sensitivity change and the time constant of recovery after bleaching were calculated by fitting an exponential equation to the data. Results-In normal subjects, neither the initial sensitivity change nor the time constant were correlated with the location of the test point. In 14 patients with ICSC, the initial sensitivity change in the detached area was significantly smaller than that in the unaVected area which was not significantly diVerent from that in the age matched normal subjects. The time constant in the detached area was significantly longer than that in the unaVected area, which was not significantly diVerent from that in the normal subjects. In 10 patients with POAG, the initial sensitivity change inside and outside the scotoma was not significantly diVerent from that of age matched normal subjects. The time constant inside the scotoma was significantly longer than that outside the scotoma, which was not significantly different from that of the age matched normal subjects. Conclusion-Both ICSC and POAG showed a prolonged time constant of recovery, but the initial sensitivity change was reduced only in ICSC. The diVerence in our results between ICSC and POAG may be caused by the diVerence of the retinal pathology. Further, the SLO-PSRT is very useful when the lesion is located outside the fovea.

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Foveal Densitometry in Central Serous Choroidopathy

Cited by 25 publications

References 5 publications

Fluorescein-Angiographic Patterns in Patients with Central Serous Chorioretinopathy at the Initial Visit

Fluorescein-Angiographic Patterns in Patients with Central Serous Chorioretinopathy at the Initial Visit

Foveal cone photopigment bleaching in central serous retinopathy

Extrafoveal photostress recovery test in glaucoma and idiopathic central serous chorioretinopathy

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