Fournier's gangrene: vacuum-assisted closure versus conventional dressings

Fournier’s gangrene: A retrospective analysis of 25 patients

“…Delays in the diagnosis and treatment, primary anorectal disease, advanced age, female gender, DM, malignant disorders, multiple organ failure at admission, and a high Fournier's gangrene index are predictors of a poor prognosis. [3,12,20] Despite advances in its diagnosis and treatment, the mortality rates associated with Fournier's gangrene remains as high as 16-50%. [2,6,10,14] Unfortunately, a 70-year-old woman with a perianal abscess and diabetes died in our study.…”

“…[2,3,12,19,20] Among these factors, DM is the most common. [2,4,6,7,9,12,13,15] Diabetes leads to increased susceptibility to infections owing to the suppression of chemotaxis, phagocytosis, and immune functions. Most of our study population (80%) was diabetic.…”

“…VAC enables more comfortable mobilization and reduces the duration of hospital stay. [4,12,[21][22][23] We performed VAC in addition to debridement in 64% of our patients. The mean duration of hospital stay was 26.43 days in our cohort, and the mean number of debridements performed was 2.81 in patients who underwent VAC.…”

“…[2,[6][7][8][9][10][11][12] Although Fournier's gangrene is more common among men and the elderly, it may affect both sexes and every age group. [5,8,9,13] The basic principles of its management include broad-spectrum antibiotics and aggressive surgical debridement.…”

Reconstruction of soft tissue defects in Fournier's gangrene at a tertiary care centre

“…7 Wound care till formal reconstruction consists of wet gauze dressings, serial debridement and vacuum assisted closure (VAC) dressings. 8 In the present study 21 patients were managed by moist, dilute betadine-saline dressings while as NPWT was utilized for wound optimization in six patients.…”