Fournier's gangrene

Yaghan, Rami J.; Al‐Jaberi, Tareq; Bani-Hani, Ibrahim

doi:10.1007/bf02237442

Cited by 104 publications

(33 citation statements)

References 60 publications

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“…Similar to other reports, cases in this series often required many operations, especially genital/perineal debridements, orchiectomy, cystostomy and/or colostomy [30,31,32,33]. Overall, 30% of survivors required ongoing care after hospital discharge.…”

Section: Discussionsupporting

confidence: 48%

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

2016

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Purpose: Case series reported 20-40% mortality rates for patients with Fournier's gangrene with some series as high as 88%. This literature comes almost exclusively from referral centers. Materials and Methods: We identified and analyzed inpatients with Fournier's gangrene who had a surgical debridement or died in the US State Inpatient Databases. Results: One thousand six hundred and forty one males and 39 females with Fournier's gangrene represented <0.02% of hospital admissions. Overall, the incidence was 1.6 cases per 100,000 males and case fatality was 7.5%. Sixty six percent of hospitals cared for no cases per year, 17% cared for 1 case per year, 10% cared for 2 cases per year, 4% cared for 3 cases per year, 1% cared for 4 cases per year, and only 1% cared for ≥5 cases per year. Teaching hospitals had higher mortality (adjusted OR 1.9) due primarily to more acutely ill patients. Hospitals treating more than 1 Fournier's gangrene case per year had an adjusted 42-84% lower mortality (p < 0.0001). Conclusions: Most hospitals rarely care for Fournier's gangrene patients. The population-based mortality rate (7.5%) was substantially lower than the case series from tertiary care centers. Hospitals that treated more number of Fournier's gangrene patients had lower mortality rates, thereby supporting the rationale that regionalized care worked well for patients with this rare disease.

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Section: Discussionsupporting

confidence: 48%

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

2016

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“…Buck's fascia surrounds the deeper structures of the penis and the periurethral region. Infection may spread from Buck's fascia to Colles' fascia and the dartos fascia especially in association with injuries [10].…”

Section: Pathophysiology and Microbiologymentioning

confidence: 99%

New Insights into the Epidemiology and Etiology of Fournier’s Gangrene: A Review of 33 Patients

et al. 2009

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“…Several definitions for Fournier's gangrene have been submitted [16], [17], [18]. In our report we used a broader definition.…”

Section: Discussionmentioning

confidence: 99%

Case series of Fournier's gangrene: Affected body surface area - The underestimated prognostic factor

Morais

Neves

Ribeiro

et al. 2017

Annals of Medicine &Amp; Surgery

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ObjectivesIdentifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools.Materials and methodsRetrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed.ResultsThe series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores.ConclusionsAffected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor.

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Fournier's gangrene

Cited by 104 publications

References 60 publications

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

Fournier's Gangrene: Epidemiology and Outcomes in the General US Population

New Insights into the Epidemiology and Etiology of Fournier’s Gangrene: A Review of 33 Patients

Case series of Fournier's gangrene: Affected body surface area - The underestimated prognostic factor

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