1999
DOI: 10.1007/bf02236224
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Fournier's gangrene after hemorrhoidectomy: Association with drug-induced agranulocytosis

Abstract: An unusual case of Fournier's gangrene after hemorrhoidectomy and drug-induced agranulocytosis, as the predisposing condition, is described. The patient had severe granulocytopenia that was attributed to the recent use of dipyrone. Together with hemodynamic resuscitation, broad-spectrum antibiotic and recombinant human granulocyte colony-stimulating factor were started. Wide surgical excision of all the gangrenous tissues, in addition to laparoscopic formation of a defunctioning sigmoid loop colostomy, was per… Show more

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Cited by 23 publications
(20 citation statements)
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“…In the second case, extensive perineal sepsis developed in a 23-year-old man 5 days after haemorrhoidectomy, and he also was treated by wide excision and colostomy 68 . This complication may have been precipitated by drug-induced agranulocytosis from previous antibacterial chemotherapy.…”
Section: Open Techniquementioning
confidence: 99%
“…In the second case, extensive perineal sepsis developed in a 23-year-old man 5 days after haemorrhoidectomy, and he also was treated by wide excision and colostomy 68 . This complication may have been precipitated by drug-induced agranulocytosis from previous antibacterial chemotherapy.…”
Section: Open Techniquementioning
confidence: 99%
“…21 In the English-language literature, there are Pain and neuritis few recent reports on the risks of metamizole and none describing pediatric patients. 16,[22][23][24] Metamizole has been banned in the United States, Canada, Japan, and many European countries but continues to be sold in Latin America, Africa, and Asia. 1 The Micromedex Drugdex lists more than 240 metamizole preparations manufactured in 18 countries.…”
Section: Discussionmentioning
confidence: 99%
“…İnkontinansın nedenleri arasında sirküler anal dilatatörün yarattığı aşırı sfinkter gerilmesi ve staplerin çıkardığı halka içinde yer alan rektal kas tabakası gösterilmektedir (13)(14). Ho ve ark.…”
Section: İstatistiksel Yöntemunclassified
“…Ho ve ark. 'ları (14), staplerle hemoroidopeksi sonrası endoanal ultrasonografiyle internal sfinkter fonksiyonlarını değerlendirmiş ve sonuçlar normal sınırlarda bulunmuştur. Altomare ve arkadaşlarının bir çalışmasında ise hastalar ameliyat öncesi ve sonrası anal manometri ve üç boyutlu ultrasonografi ile değerlendirilmiş, sonuçta sfinkter hasarı saptanmamıştır (15).…”
Section: İstatistiksel Yöntemunclassified
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