Fournier's Gangrene

Campbell, JohnC.

doi:10.1111/j.1464-410x.1955.tb03450.x

Cited by 51 publications

(13 citation statements)

References 5 publications

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“…Epidermal and dermal necrosis and thrombosis from obliterative endarteritis 4 are similar to that observed in necrotizing fasciitis in other areas. Epidermal and dermal necrosis and thrombosis from obliterative endarteritis 4 are similar to that observed in necrotizing fasciitis in other areas.…”

supporting

confidence: 64%

Fournier's Syndrome in a Ketoacidotic Diabetic Patient After Intrascrotal Insulin Injections Because of Impotence

O’Dell¹,

Shipp²

1983

Diabetes Care

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Fournier's syndrome is a necrotizing fasciitis most commonly confined to the male genitalia with high morbidity and mortality rates. The salient features are (1) sudden explosive illness in the midst of apparent health; (2) rapid necrosis and sloughing of tissues of the scrotum and penis; (3) absence of an obvious cause; (4) a mixed bacteriologic picture; and (5) gangrene affecting the whole thickness of the scrotal skin, but not the underlying testes. With the propensity toward life-threatening infections in patients with diabetes, it is surprising that Fournier's syndrome is not more common in suboptimally treated diabetic patients. This report is to illustrate the recognition and treatment of Fournier's syndrome in a patient with diabetes. Also, it must be emphasized that the explosive course of the disease process begins with a benign-appearing, epididymitis-like picture. Prompt recognition followed by prompt surgical debridement and appropriate antibiotic therapy along with surgical wound closure is necessary to reduce morbidity and mortality. The present case is unusual for the following reasons: (1) necrosis of the testicles requiring orchiectomy; (2) extensive spread of gangrene beyond the genitalia; and (3) the route of infection, which appeared to be intrascrotal injections of insulin in a vain attempt to cure impotence.

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supporting

confidence: 64%

Fournier's Syndrome in a Ketoacidotic Diabetic Patient After Intrascrotal Insulin Injections Because of Impotence

O’Dell¹,

Shipp²

1983

Diabetes Care

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“…While there are reports on spontaneous healing using dressing alone [57][58][59], other authors insist on avoiding spontaneous healing because it can lead to further complications [47,86], requiring additional reconstructive procedures [72,87]. Although the inflammatory process usually affects the borderlines to healthy organs, testicular abscess and gangrene on the one hand, or penis gangrene on the other hand may result in loss of testes and penis in few patients [88][89][90][91].…”

Section: Morbidity and Complicationsmentioning

confidence: 99%

Necrotizing Fasciitis of the Perineum and the Abdominal Wall-Surgical Approach

Ecker¹,

Baars²,

Töpfer³

et al. 2008

Eur J Trauma Emerg Surg

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Necrotizing fasciitis is a synergistic aerobical-anaerobical infection that rapidly spreads from its origin leading to foudroyant increasing soft tissue gangrene and systemic sepsis. In the perineal, perianal and genital regions it is referred to as Fournier's gangrene constituting a clinical entity with the gangrene of the abdominal wall. After a short presentation of the own experience with 17 patients the surgical approach to the life-threatening disease is presented reviewing the former and the recent literature. There is a worldwide consensus that immediate radical excision of the gangrene should be accompanied by intensive care measures. Functional and cosmetic defects are to be reconstructed in a second stage. However, morbidity and mortality remain high in spite of consequent treatment due to often associated significant co-morbidity of affected patients.

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“…PATHOLOGY.-~ infective obliterative endarteritis occurs due to spread of organisms within the fatty subcutaneous tissues, and causes ischaemic necrosis of the overlying skin (Campbell, 1955). The haemolytic streptococcus is often present, other possible organisms including Staphylococcus aureus in symbiosis with an anaerobic streptococcus (Ebrill and O'Donoghue,I951), Bacillus coli, fusiforms, Clostridium welchii, Pseudomonas pyocyanea, and P .…”

Section: Discussionmentioning

confidence: 99%

“…Lastly, some describe the condition as originating in a suppurative peri-urethritis and adenitis (of Cowper's and Littre's glands). As regards age, gangrene of the scrotum has been seen at all ages from 4 days to 80 years (Campbell, 1955).…”

Section: Discussionmentioning

confidence: 99%