Fourier Transform Time-of-Flight Mass Spectrometry in an Electrostatic Ion Beam Trap

Ring, Sven; Pedersen, H. B.; Heber, O.; Rappaport, Michael; Witte, P. D.; Bhushan, K. G.; Altstein, N.; Rudich, Yinon; Sagi, Irit; Zajfman, D.

doi:10.1021/ac000317h

Cited by 37 publications

(22 citation statements)

References 39 publications

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“…5 Schematic of the Aerosol Impact Spectrometer data acquisition and computer control system trapped. The m/z ratio of the particle in the trap is determined from its oscillation frequency, f, using the following relationship [1,26]:…”

Section: Nanoparticle Electrostatic Trapmentioning

confidence: 99%

“…This method has been used in accelerator experiments since at least 1960 [9], and with the increasing interest in studies of massive biomolecules, cells and nanoparticles it has seen more recent applications in mass spectrometry measurements [16][17][18][19][20][21][22][23][24], with the state of the art recently described by Keifer and Jarrold [25]. In our own laboratory, we make use of a variant of this approach, applying a charge-pickup electrode in an electrostatic fast-ion beam trap to monitor the ion density oscillating in the trap and carry out Fourier-transform (FT) mass spectrometry on ensembles of molecular ions [26,27]. In the present apparatus the m/z ratio of a single particle provides the information required to accelerate or decelerate that particle for studies of particle impact.…”

Section: Introductionmentioning

confidence: 99%

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The aerosol impact spectrometer: a versatile platform for studying the velocity dependence of nanoparticle-surface impact phenomena

2017

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A new apparatus designed to accelerate/decelerate and study the surface impact phenomena of charged aerosols and nanoparticles over a wide range of mass-tocharge (m/z) ratios and final velocities is described. A nanoparticle ion source coupled with a linear electrostatic trap configured as an image charge detection (ICD) mass spectrometer allows determination of the mass-to-charge ratio and the absolute charge and mass of single nanoparticles. A nine-stage linear accelerator/ decelerator is used to fix the final velocity of the nanoparticles, and in the results reported here the coefficient of restitution for polystyrene latex spheres (PSLs) impacting on silicon is measured using ICD techniques. To enable this apparatus to study a wide range of m/z, the data acquisition system uses a transient digitizer interfaced to a field-programmable gate array module that allows real time calculation of m/z and determination of the pulse sequence for the linear accelerator/decelerator. Electrospray ionization of a colloidal suspension of PSL spheres of 510 and 990 nm has been used to demonstrate acceleration and deceleration of charged nanoparticles and the resolution of the apparatus. Measurements of the coefficient of restitution for PSLs on silicon over the range 10-400 m/s are consistent with previous studies.

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Section: Nanoparticle Electrostatic Trapmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The aerosol impact spectrometer: a versatile platform for studying the velocity dependence of nanoparticle-surface impact phenomena

2017

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“…With appropriate choices of γ and c, CHIMERA could also be easily applied to other electrostatic traps and rings for which ion bunches are injected from an external source. For instance, ion bunches from a matrix-assisted laser desorption and ionization source 19 and a pulsed beam 20 have previously been injected into this type of trap using electrostatic optics. Another possible implementation would be for the case where ions are confined and cooled in a radiofrequency trap prior to injection into a storage ring, provided the ions are injected directly rather than being mass selected by a magnet.…”

Section: Discussionmentioning

confidence: 99%

A comb-sampling method for enhanced mass analysis in linear electrostatic ion traps

Greenwood

Kelly

Calvert

et al. 2011

Review of Scientific Instruments

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In this paper an algorithm for extracting spectral information from signals containing a series of narrow periodic impulses is presented. Such signals can typically be acquired by pickup detectors from the image-charge of ion bunches oscillating in a linear electrostatic ion trap, where frequency analysis provides a scheme for high-resolution mass spectrometry. To provide an improved technique for such frequency analysis, we introduce the CHIMERA algorithm (Comb-sampling for High-resolution IMpulse-train frequency ExtRAaction). This algorithm utilizes a comb function to generate frequency coefficients, rather than using sinusoids via a Fourier transform, since the comb provides a superior match to the data. This new technique is developed theoretically, applied to synthetic data, and then used to perform high resolution mass spectrometry on real data from an ion trap. If the ions are generated at a localized point in time and space, and the data is simultaneously acquired with multiple pickup rings, the method is shown to be a significant improvement on Fourier analysis. The mass spectra generated typically have an order of magnitude higher resolution compared with that obtained from fundamental Fourier frequencies, and are absent of large contributions from harmonic frequency components.

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“…The application of our trap as a folded, time-of-flight (TOF) mass spectrometer, albeit without self-bunching, has been previously described [9]. A mass resolution of m/m = 3.5 × 10 −4 for m = 40 was obtained.…”

Section: Discussionmentioning

confidence: 99%

Self-bunching induced by negative effective mass instability in an electrostatic ion beam trap

Strasser

Heber

Goldberg

et al. 2003

J. Phys. B: At. Mol. Opt. Phys.

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We demonstrate that the synchronization effect, which has been observed when a bunch of ions oscillates between two mirrors in an electrostatic ion beam trap, can be explained as a negative effective mass instability. We derive simple necessary conditions for the existence of a regime in which this dispersionless behaviour occurs and demonstrate that, in this regime, the ion trap can be used as a high resolution mass spectrometer.

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Fourier Transform Time-of-Flight Mass Spectrometry in an Electrostatic Ion Beam Trap

Cited by 37 publications

References 39 publications

The aerosol impact spectrometer: a versatile platform for studying the velocity dependence of nanoparticle-surface impact phenomena

The aerosol impact spectrometer: a versatile platform for studying the velocity dependence of nanoparticle-surface impact phenomena

A comb-sampling method for enhanced mass analysis in linear electrostatic ion traps

Self-bunching induced by negative effective mass instability in an electrostatic ion beam trap

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