Fourier-transform infrared spectroscopic study of characteristic molecular structure in cancer cells of esophagus: An exploratory study

Maziak, Donna E.; Do, Minh T.; Shamji, Farid M.; Sundaresan, Sudhir; Perkins, D. Garth; Wong, P. T. T.

doi:10.1016/j.cdp.2007.03.003

Cited by 106 publications

(61 citation statements)

References 32 publications

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“…10. FtiR spectra for normal and cancer sputum Adapted from lewis P. and lewis K. (24) the expected differences in absorbance bands between cancer and normal spectra in the region of proteins, carbohydrates and nucleic acids were confirmed (32,47,54). the peaks at 1656 cm -1 and 1577 cm -1 in the amide i and amide ii regions in all spectra in normal and cancer cells had changed intensities.…”

Section: Analyses Of Lung Cancermentioning

confidence: 80%

“…the small band at 964 cm -1 , due to c-c stretching vibration in nucleic acids (28) and symmetrical stretching mode of dianionic phosphate monoesters of phosphorylated proteins (32) in normal samples shifted to the 966 cm -1 in cancer sputum. the intensity of the peaks at 1024 cm -1 and 1049 cm -1 , associated with the c-o stretching and c-o bending vibration of glycogen (32) were increased in all cancer cells.…”

Section: Analyses Of Lung Cancermentioning

confidence: 92%

“…the band at 1656 cm -1 for amide i associated with νC=O vibration shifted at 1654 cm -1 in cancer sputum cells. the band at 1577 cm -1 for amide II was associated with νC-N, and δNH vibration (32). The documented infrared spectra in the protein region for adenocarcinoma and squamous cell carcinoma were the same, therefore, different types of lung cancer could not be distinguished.…”

Section: Analyses Of Lung Cancermentioning

confidence: 95%

“…in addition, the frequencies shifted to 1239.4 cm -1 , and 1085.1 cm -1 in malignant tissues. The enlarged spectra of the ν as Po 2 -band, mainly originated from the phosphodiester backbone of cellular nucleic acids (32,47,54) for normal and malignant colonic tissues and are plotted together at Fig. 1.…”

Section: Application Of Fourier Transform Infrared Spectroscopy For Tmentioning

confidence: 99%

“…the enlarged infrared spectra of the normal and malignant tissues are shown at Fig. 5, where the two major bands at 1078 cm -1 and 1238 cm -1 , are due to the symmetric and asymmetric stretching modes of the phosphodiester groups of cellular nucleic acids (32,37,47,54). Adapted from Ranjana M. and Gunjan t. (41) the band at 1078 cm -1 of normal tissue shifted to 1069 cm -1 in the malignant tissue and the peak intensity increased.…”

Section: Application Of Fourier Transform Infrared Spectroscopy For Tmentioning

confidence: 99%

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Application of Fourier Transform Infrared Spectroscopy for Tumor Diagnosis

Simonova

Karamancheva

2013

Biotechnology & Biotechnological Equipment

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Section: Analyses Of Lung Cancermentioning

confidence: 80%

Section: Analyses Of Lung Cancermentioning

confidence: 92%

Section: Analyses Of Lung Cancermentioning

confidence: 95%

Section: Application Of Fourier Transform Infrared Spectroscopy For Tmentioning

confidence: 99%

Section: Application Of Fourier Transform Infrared Spectroscopy For Tmentioning

confidence: 99%

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Application of Fourier Transform Infrared Spectroscopy for Tumor Diagnosis

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2013

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Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Depciuch

Stec

Maximenko

et al. 2020

Applied Organom Chemis

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One of the most common anticancer therapies is photothermal therapy (PTT). The effectiveness of PTT depends on the photosensitizer being a molecule which is toxic for the cancer cells after electromagnetic wave irradiation. Therefore, a simulation of PTT was performed in this work on two colon cancer cells (SW480 and SW620) using platinum nanoparticles (Pt NPs). Interestingly, in the literature the dependence between the synthesis method and the photothermal properties of Pt NPs was not discussed. Consequently, in this paper, we evaluated the photothermal properties of Pt NPs synthesized by two different methods: polyol (PtI NPs) and green chemistry (PtII NPs). Scanning transmission electron microscopy revealed that the size of both Pt NPs obtained was 2 nm, the NPs were not agglomerated, and that the PtII NPs were distributed on green tea supports. The selected area electron diffraction and X‐ray diffraction analysis confirmed the crystallinity of both types of Pt NPs. Fourier‐transform infrared (FTIR) spectrum of the PtII NPs showed interactions between the NPs and stretching modes for C=O groups from flavonoids and polyphenols. Therefore, these chemical compounds could be responsible for reducing Pt4+ ions to Pt0. Moreover, the 3‐(4,5‐dimethylthiazol‐2‐yl)‐5‐(3‐carboxymethoxyphenyl)‐2‐(4‐sulfophenyl)‐2H‐tetrazolium (MTS) assay showed that the PtII NPs exhibited 10% and 20% better cytotoxicity effect on SW480 and SW620 cells, than PtI NPs. The viability of cancer cells decreased when Pt NPs were used in PTT. The highest percentage of dead cells (82%) was observed for PtII NPs and 650‐nm laser irradiation. FTIR and Raman spectroscopy showed structural changes induced by both Pt NPs and laser irradiation of cells in the range corresponding to levels of DNA, phospholipids, proteins, and lipids. Moreover, the calculated photothermal conversion efficiency showed that the value of this parameter is around 35%, regardless of the synthesis method and used wavelengths.

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Different experimental approaches for Fourier‐transform infrared spectroscopy applications in biology and biotechnology: A selected choice of representative results

Errico

Moggio

Diano

et al. 2022

Biotech and App Biochem

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Fourier transform infrared (FTIR) spectroscopy is a powerful tool for analyzing the biochemical properties of biological samples such as proteins, cellular materials, and tissues. It provides objective information on samples and has been adopted in many research areas of biomedical and biotechnological interest. FTIR spectroscopy can be performed using different approaches at the macro and micro levels allowing the examination of an incredibly broad class of materials. However, it has become evident that the choice of proper spectra acquisition geometries and the modalities of sample preparation in FTIR spectroscopy analysis require special consideration, especially for certain classes of materials such as cells and tissues. In the present paper, we described the different procedures used for preparing and analyzing different types of biological and biotechnological samples when the more largely available approaches are employed using a commercial FTIR spectrometer. Some basic aspects of data analysis procedures are presented in an Appendix. A certain number of our previous experimental results are reported for demonstrating once more the versatility and the potentiality of FTIR spectroscopy.

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Fourier-transform infrared spectroscopic study of characteristic molecular structure in cancer cells of esophagus: An exploratory study

Cited by 106 publications

References 32 publications

Application of Fourier Transform Infrared Spectroscopy for Tumor Diagnosis

Application of Fourier Transform Infrared Spectroscopy for Tumor Diagnosis

Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Different experimental approaches for Fourier‐transform infrared spectroscopy applications in biology and biotechnology: A selected choice of representative results

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