Fourier polarimetry of human skin in the tasks of differentiation of benign and malignant formations

Abstract

The optical model of polycrystalline networks of human tissue has been proposed. The values of statistical parameters (statistical moments of the first to fourth order) characterizing the polarization-inhomogeneous images of skin surface in the Fourier domain have been measured. The diagnostic criteria of pathological processes in human skin and the differentiation of its severity degree have been determined.

Scale-selective wavelet differentiation of layered phased maps of polarization azimuth for images of biological crystal networks

“…The experimental studies were conducted in an optical setup of a polarization interferometer, the description of which is provided in the series of publications [1][2][3][4][5][6][7][8][9][10][11] .…”

Integrative pathophysiological and correlation-optical study of the kidneys for the formation of tubulo-interstitial syndrome: part 1–polarization and birefringence structure

“…The experiments were performed on 32 white nonlinear male rats weighing 0.16-0.18 kg in the hyposodiumdiet. Tubulointerstitial syndrome was modeled by a single injection of corrosive sublimate subcutaneously at a dose of 5 mg/kg body weight with a study on the 30 th day of the polyuric stage of nephropathy, for which the formation of this syndrome [1][2][3][4][5][6][7][8][9] . Renal function was studied by injecting rats with tap water 5% of body weight in the stomach with a metal probe, followed by urine collection for 2 hours.…”

“…A marker of collagen synthesis is oxyproline, which allows the quantitative determination of this amino acid to judge the degree of collageno genesis [4]. In the tubule sof the renal cortex of the kidneys shows high activity of the Krebs cycle enzymesuccinate dehydrogenase, which characterizes the energy state of the tubules and is very sensitive to damage [5,6,[7][8][9][10][11][12][13][14][15][16][17][18][19][20].…”

Legal aspects of the development of optical medicine for severe systemic diseases

“…The number of people suffering from joint disease is projected to only increase in the future, with the fastest growing rates in low-and middle-income countries 2 . In Ukraine, more than 80% of the population suffer from pathologies of the musculoskeletal system, 90% of children have postural disorders, and 20% are diagnosed with scoliosis [3][4][5][6][7][8][9][10] . From a physical point of view, such a problem lies in the fact that it is scientifically relevant: -formation of relationships between the structure of polycrystalline networks of films of biological fluids and layer-by-layer distributions of azimuthally invariant Mueller-matrix maps, elements of polarized (polarization-phase tomogram) and depolarized (diffusion tomogram) components of the differential matrix; -development of methods for multi-parameter statistical, correlation and fractal processing of experimentally obtained polarization-phase and diffusion tomograms of optically anisotropic structure of prototypes and determination of a set of new objective criteria for early detection of pathologies of human organism.…”