Fourier Domain Optical Coherence Tomography for Retinal Imaging with 800-nm Swept Source: Real-time Resampling in k-domain

Lee, Sang-Won; Song, Hyunwoo; Kim, Bong-Kyu; Jung, Man‐Young; Kim, Seunghwan; Cho, Jae Du; Kim, Chang-Seok

doi:10.3807/josk.2011.15.3.293

Cited by 11 publications

(8 citation statements)

References 36 publications

(47 reference statements)

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“…Therefore, an 800-nmcentered swept laser can be a versatile source for molecular optical spectroscopic imaging such as SOCT, near-infrared spectroscopy, diffuse optic imaging, fluorescence imaging [13] and spectrally encoded confocal microscopy [14]. While several research groups have demonstrated a swept laser near 800 nm [15][16][17][18][19][20][21], this is the first time a swept laser centered at 800 nm has been used in SOCT imaging to obtain functional information.…”

Section: Introductionmentioning

confidence: 99%

800-nm-centered swept laser for spectroscopic optical coherence tomography

2014

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The isosbestic point of oxy-and deoxy-hemoglobin at 800 nm is an important point in biomedical optical spectroscopic imaging. We have developed a novel swept laser centered at 800 nm and demonstrated its performance for spectroscopic optical coherence tomography. The measured −10 dB spectral bandwidth of the swept laser was 40 nm and averaged laser output power per sweep was 4 mW. This swept laser was incorporated into our OCT system and used to measure non-scattering liquid phantoms and blood samples. The measured maximum sensitivity and roll-off rate over a range of image depths were 112 dB and −1.45 dB mm −1 , respectively. The minimum axial resolution of the OCT system was 8.06 µm at a depth of 2.4 mm. Quantitative and localized absorption spectra were recovered from the non-scattering liquid phantoms. In addition, the measured localized wavelength-dependent attenuation difference of oxygenated and deoxygenated blood was 4.6-fold.

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Section: Introductionmentioning

confidence: 99%

800-nm-centered swept laser for spectroscopic optical coherence tomography

2014

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“…Also, the WSL with a FFP-TF had a nonlinear response in the wave-number domain, since the response of the piezoelectric transducer in the FFP-TF has a nonlinear response to a sinusoidal modulation signal. Therefore, it requires a recalibration process in the wave-number domain [27–30]. …”

Section: Introductionmentioning

confidence: 99%

Dynamic Sensor Interrogation Using Wavelength-Swept Laser with a Polygon-Scanner-Based Wavelength Filter

Kwon

Jung

et al. 2013

Sensors

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We report a high-speed (∼2 kHz) dynamic multiplexed fiber Bragg grating (FBG) sensor interrogation using a wavelength-swept laser (WSL) with a polygon-scanner-based wavelength filter. The scanning frequency of the WSL is 18 kHz, and the 10 dB scanning bandwidth is more than 90 nm around a center wavelength of 1,540 nm. The output from the WSL is coupled into the multiplexed FBG array, which consists of five FBGs. The reflected Bragg wavelengths of the FBGs are 1,532.02 nm, 1,537.84 nm, 1,543.48 nm, 1,547.98 nm, and 1,553.06 nm, respectively. A dynamic periodic strain ranging from 500 Hz to 2 kHz is applied to one of the multiplexed FBGs, which is fixed on the stage of the piezoelectric transducer stack. Good dynamic performance of the FBGs and recording of their fast Fourier transform spectra have been successfully achieved with a measuring speed of 18 kHz. The signal-to-noise ratio and the bandwidth over the whole frequency span are determined to be more than 30 dB and around 10 Hz, respectively. We successfully obtained a real-time measurement of the abrupt change of the periodic strain. The dynamic FBG sensor interrogation system can be read out with a WSL for high-speed and high-sensitivity real-time measurement.

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“…The The output of the Michelson interference is nothing but the interference pattern in the form of fringes. The interference pattern has the optical light; this optical intensity is measured by the spectrometer (Lee et al, 2011). As for image formation FFT is taken and for which the data must be evenly sampled in wavenumber space, for this resampling and interpolation blocks are followed.…”

Section: Formation Of B-scan Imagementioning

confidence: 99%

“…This data is then taken for the signal processing for the image formation (Tang et al, 2018). Figure 1 describes the working principle of Michelson Interferometer, where half-silvered beam splitter is used (Kim et al, 2018;Lee et al, 2011). Bhatia et al (2016) described the core of the OCT systems and implemented the spectral-domain OCT(SD-OCT).…”

Section: Introductionmentioning

confidence: 99%

Algorithm for B-scan Image Reconstruction in Optical Coherence Tomography

Patil¹,

Mahajan²,

Subramani³

et al. 2021

JST

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Optical coherence tomography (OCT) is an evolving medical imaging technology that offers in vivo cross-sectional, sub-surface images in real-time. OCT has become popular in the medical as well as non-medical fields. The technique extensively uses for food industry, dentistry, dermatology, and ophthalmology. The technique is non-invasive and works on the Michelson interferometry principle, i.e., dependent on back reflections of the signal and its interference. The objective is to develop an algorithm for signal processing to construct an OCT image and then to enhance the quality of the image using image processing techniques like filtering. The image construction was primarily based on the Fourier transform (FT) of the dataset obtained by data acquisition. This FT could be performed rapidly with the extensively used algorithm of fast Fourier transform (FFT). The depth-wise information could be extracted from each A-scan, i.e., axial scan and also the B-scan was obtained from the A-scan to see the structure of sample. The maximum penetration depth achieved with proposed system was 2.82mm for 1024 data points. First and second layer of leaf were getting at thickness of 1mm and 1.6mm, respectively. A-scans for Human fingertip gave its first, second and third layer was at a thickness of 0.75mm, 0.9mm and 1.6mm, respectively. A-scans for foam sheet gave its first, second and third layer was at a thickness of 0.6mm, 0.75mm, and 0.85mm, respectively.

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Fourier Domain Optical Coherence Tomography for Retinal Imaging with 800-nm Swept Source: Real-time Resampling in k-domain

Cited by 11 publications

References 36 publications

800-nm-centered swept laser for spectroscopic optical coherence tomography

800-nm-centered swept laser for spectroscopic optical coherence tomography

Dynamic Sensor Interrogation Using Wavelength-Swept Laser with a Polygon-Scanner-Based Wavelength Filter

Algorithm for B-scan Image Reconstruction in Optical Coherence Tomography

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