Four pregnane glycosides, boucerosides AI, AII, BI and BII, from Boucerosia aucheriana

Three New Pregnane Glycosides from Marsdenia tinctoria

“…Those findings suggested that the unidentified sugar is 6-deoxy-3-O-methyl-b-d-allose (3-O-methyl-b-d-allomethylose) on the basis of its 1 H-and 13 C-NMR assignments, which are in agreement with those of similar compounds [4] [7]. The existence of one doleandropyranosyl and three d-cymaropyranosyl units were confirmed by comparison of their spectroscopic data with those in the literature [4] [8]. Further, the chemical- shift values for C(2') (d(C) 37.3), C(2'') (d(C) 37.0), and C(2''') (d(C) 36.1) of the three cymarose units as well as C(2'''') (d(C) 37.7) of the oleandrose unit present in 1 showed that they all have d-configuration [9].…”

“…Mild acid hydrolysis of 3 yielded stephanthraniline A (5) as the aglycone, as well as cymarose, oleandrose, 3-O-methylallomethylose, and glucose as the sugar moieties. The comparison of the 13 C-NMR spectral data of 3 ( Table 2) with those of bouceroside indicated that 3 possessed the same sugar sequence in the oligosaccharide moiety as bouceroside [8]. The position of each sugar residue was further confirmed by a 2D-ROESY experiment, which showed a cross-peak between the signal at d(H) 5.26 (HÀC(1')) and the signal at d(H) 3.78 -3.86 (HÀC(3)), and other key correlation peaks between the signals at d(H) 4.66 (HÀC(1'')) and 3.44 -3.50 (HÀC(4')), 5.25 (HÀC(1''')) and 3.50 -3.58 (HÀC(4'')), 4.97 (HÀC(1'''')) and 3.74 (HÀC(4''')).…”

A new pregnane steroid from the stems ofCaralluma umbellata

“…Carumbelloside-I (3), isolated from C. umbellata, exhibited significant analgesic activity and antimicrobial activity [3]. A survey of the literature revealed that species of the genus Caralluma have been investigated on alcoholic extracts and found to be a source of steroids, triterpenes, and steroidal glycosides [4][5][6][7][8][9][10][11][12][13]. The isolation and structural elucidation of three pregnane glycosides 2, 3, and 4 and one flavanone glycoside luteolin-4-Oneohesperidoside were reported from C. umbellata [14].…”

Anti bacterial effect of ethanolic leaf extract of caralluma fimbriataon e.faecalis -an invitro study

“…Results: Different concentrations of the extract (200mg/mL showed dose dependant antibacterial activity and the MBC was found to be more than 400 mg/ mL Conclusion: This study suggests that the Ethanolic extract of leafcontains promising antibacterial substances which is having activity against is a succulent plant in the family has been eaten in rural India for centuries, as a raw vegetable with spices, or preserved in chutneys and pickles and is often found as a Caralluma fimbriata contains pregnane glycosides, a phytochemical that blocks the When this enzyme's activity is stopped, Caralluma Fimbriata blocks the enzymes responsible for breaking down and producing [2]. The main photochemicals in are pregnane glycosides [3,4] flavone glycosides , megastigmane glycosides [5], bitter principles,…”