Four cases of mucous membrane pemphigoid with clinical features of oral lichen planus

Abstract

Because MMP and OLP require different treatments, all dentists and dermatologists should have knowledge about the disease entity and the serological diagnostic methods for various types of MMP.

Comments regarding “Four cases of mucous membrane pemphigoid with clinical features of oral lichen planus” and on the utility of immunofluorescence

“…Thus, given the often innocuous clinical appearance of oral LPP that resembles oral LP, as noted in our own clinical experiences as well as that of Fukuda et al , we would like to emphasize the importance of immunofluorescence studies to establish a diagnosis of LPP to ensure a prompt referral to the appropriate specialists to prevent debilitating sequelae secondary to mucosal scarring.…”

“…Contributing to its lack of recognition, oral LPP is likely frequently underdiagnosed due to the lack of prescribed immunofluorescence studies in cases that may appear similar to oral LP. Including the recently published findings of Fukuda and colleagues, there are now 35 reported cases of LPP with well‐characterized oral involvement that have undergone confirmatory testing with direct immunofluorescence, 31 (89%) of which presented clinically with classic reticular or erosive LP with an absence of intraoral bullae . While we recognize that oral lesions of both diseases are treated in a similar manner, the utility of immunofluorescence studies in establishing the diagnosis of oral LPP is of importance, as LPP is considered a systemic autoimmune disease within the pemphigoid family that may present with a scarring phenotype affecting the conjunctivae, larynx, and/or esophagus, which carries a risk of progression to complications such as blindness, respiratory distress, and dysphagia, respectively …”

“…We congratulate Fukuda et al for an excellent illustration of a series of cases representing a relatively rare entity that is oral lichen planus pemphigoides (LPP). We further commend the authors for highlighting the importance of a comprehensive workup, including laboratory studies of immunofluorescence and ELISA, as part of the evaluation of what may appear to be a clinically banal case of oral lichen planus.…”

Linear Iga Bullous Dermatosis Mimicking Oral Lichen Planus

“…In recent years, indirect and direct immunofl uorescence have emerged as tools that can be used in conjunction with histopathology in making these diffi cult diagnoses (5). It is important to consider oral LABD as a diff erential in cases of clinically suspected oral lichen planus, especially those that fail to respond to initial therapies.…”

Comments regarding “four cases of mucous membrane pemphigoid with clinical features of oral lichen planus”

“…We read the recent article by Fukuda et al with great enthusiasm. In this article the authors reported the oral lichen planus (OLP)‐like presentation of mucous membrane pemphigoid (MMP).…”