The present work aims to study the influences of depth and orientation on the distribution of macrofouling communities at shallow coastal harbour (Abu Qir Harbour, Egypt, southeast Mediterranean Sea). Fouling communities were collected for a period of one year (June 2006-May 2007) by suspended white test panels at different depths (from 0.5 m to 5.5 m) in two directions (horizontal and vertical). Panels were submerged on short-term durations of 30 days. Every panel was studied (on both sides) for species composition and abundance of fouling taxa, as well as the total biomass of the community. Data of fouling assemblages obtained were analysed using ANOVA and non-parametric tests in order to compare the variations of assemblages with season, depth and direction. In general, the abundance and biomass of fouling community were significantly related to the season and depth rather than orientation. Although comparison of fouling assemblages (for direction) between the panel surfaces were not statistically significant; the horizontal panels, in particular, support more fouling organisms.