Abstract:This study was carried out to create an emulsion formulation based on Celecoxib in order to improve its solubility. The solubility of Celecoxib in different surfactants and co-surfactants was studied. Secondly, pseudo-ternary phase diagrams were used to fix the concentration ranges of the components of the emulsion. Once the most stable formulation was fixed by mixture design, the concentration of solubilized Celecoxib in this formulation was determined using UV-visible spectrophotometry. The concentration of … Show more
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