Abstract:Dicyclomine hydrochloride have major problem to its bitter taste. Due to its bitter taste pediatric and geriatric patients have less acceptability. The objective of present work was preparation and evaluation of chewable tablets of Dicyclomine hydrochloride by using Ion exchange resin for taste masking. Taste masking of Dicyclomine HCl was done by using weak cation exchange resin such as Tulsion 335 and Kyron T 159. When comparing drug loading capacity it noticed that Tulsion 335 showed high drug loading as co… Show more
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