Formulation and Release Kinetics of Sustained Release Phenylpropanolamine Hydrochloride Granules and Tablets

Abstract

S u :< c i! i 11 ed re 1 e a 3 c? p h en y l p r o p a n o 1 a m i n e h y d r o ch 1 I ' i de i F E ' H ) g r a : i u I r~s a n d t a b l e t s were p r e p a r e d u s i n g HI'hlC,T h e r e 1 e a s e p a t t e r n of YE11 f r V , i i t t i z p r e p a r e d g r a n u l e s a n d t a b l e t s w a s f o u n d t o b e i n the following o r d e r HPMCHPMC t SCMC > RS > R S t I .~ HPMC + I NTRODUCT I ON Although the intensity of a pharmacological effect is related to the drug concentration at the site of act-1795 Copyright 0 1994 by Marcel Dekker, Inc. Drug Dev Ind Pharm Downloaded from informahealthcare.com by University New South Wales on 08/21/15 For personal use only.