Abstract:Diclofenac sodium is a non steroidal anti-inflammatory agent used in the treatment of many diseases including rheumatoid arthritis and ankylosing spondylitis . This investigation concerned with the preparation and evaluation of diclofenac sodium as conventional suppositories to achieve optimum drug release at a rectal route.The influence of suppository base type on the in vitro release of the drug and the physical properties was studied using various hydrophilic and lipophilic bases in the preparation of conve… Show more
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