Formulation and in-vitro Evaluation of Vildagliptin Microspheres Using Pectin and Xanthan Gum as Polymers
KRISHNAVENI MANUBOLU,
RAVEESHA PEERIGA,
KUDIPUDI HARINADHA BABA
et al.
Abstract:Aim
The aim of the work is a formulation and in vitro evaluation of the vildagliptin microsphere using pectin and xanthan gum.
Objective
Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor extensively associated with the therapy of type-2 diabetes mellitus. A controlled release of the drug in the gastrointestinal tract may aid in maintaining the therapeutic range for an extended period. Sodium alginate, pectin, and xanthan gum are commonly used as biopolymers in drug delivery with favourable biocompat… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.