Formulation and Evaluation of <i>Amomum sublatum</i> Leaf Oil Incorporated Pluronic Matrix Type Transdermal Patches in Percutaneous Absorption
Sudip Das,
Bapi Ray Sarkar,
Koushik Sen Gupta
Abstract:A matrix type of transdermal patch formulations having different types of hydrophilic, hydrophobic polymer components Diclofenac potassium (Diclofenac K) served as the model drug and penetration enhancer for topical delivery in this research, employing the USP7 apparatus for dissolution studies. Transdermal patches loaded with Amomum sublatum leaf volatile oil (utilized penetration enhancer) were formulated using the solvent evaporation technique, incorporating varying amounts of pluronic F-127 and ethyl cellu… Show more
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