Formulation and evaluation of herbal antioxidant face cream of Nardostachys jatamansi collected from Indian Himalayan region

Mishra, Abhay Prakash; Saklani, Sarla; Milella, Luigi; Tiwari, Priyanka

doi:10.12980/apjtb.4.2014apjtb-2014-0223

Cited by 35 publications

(28 citation statements)

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“…Dispersion Stability Tests: 4 To evaluate the physical stability of the formulations, thermodynamic stability tests were performed. Selected formulations were subjected to different thermodynamic stability tests to overcome the problem of metastable formulations.…”

Section: Preparation Of Centella Asiatica Extract Containing Nanoemulmentioning

confidence: 99%

Untitled

2019

IJPSR

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Centella asiatica L. Urban (family: Umbelliferae) contains several active triterpenoids which have been reported to induce type I collagen which decreases substantially in photoaged skin. Centella asiatica extract is highly soluble in water but have low absorption into the skin. To overcome this, water in oil nanoemulsion loaded with Centella asiatica extract have been formulated, optimized and evaluated as the potential delivery system for treating photoaging. Nanoemulsions were formulated by the oil phase titration method and optimized by constructing pseudo-ternary phase diagrams. The prepared nanoemulsions were subjected to thermodynamic stability testing. Those that passed these tests were characterized for droplet size, polydispersity index, zeta potential and droplet morphology by Cryo-SEM. The prepared nanoemulsions were in nanometric range (optimized batch: 140.5 nm) with uniform size distribution (PDI: 0.086) and good physical stability (zeta potential: -33.9 mV). Topical permeation of Centella asiatica loaded nanoemulsion through porcine abdominal skin was estimated using the Franz diffusion cell. A significant increase in permeability parameters was observed in nanoemulsion formulations (P<0.05) as compared to an aqueous solution of Centella asiatica extract. Topical application of CA nanoemulsion loaded cream to rat hind limb significantly reduced the wrinkle formation on UV exposed skin. Histopathological studies of the skin samples further confirmed the antiphotoaging effects of the prepared nano-emulsion formulation.

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Section: Preparation Of Centella Asiatica Extract Containing Nanoemulmentioning

confidence: 99%

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2019

IJPSR

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“…The effect of parameters such as the content of surfactant, oil, herbal extracts, HLB number of surfactant blend and additive content on emulsion stability was studied by trial and error method [9][10][11]. Formulations with selected herbal ingredients were prepared by the emulsion method to obtain o/w emulsion formulations.…”

Section: Preparation Of Formulationsmentioning

confidence: 99%

“…Formulations with selected herbal ingredients were prepared by the emulsion method to obtain o/w emulsion formulations. St John's wort extract, marigold extract, wheat germ oil, rose oil, ascorbyl palmitate, cetyl alcohol, liquid paraffin were used as oil phase [9]. Span 80 ® was used as hyrophobic surfactant and mixed with oil phase with a magnetic stirrer (RH basic, IKA, Staufen, Germany).…”

Section: Preparation Of Formulationsmentioning

confidence: 99%

“…In this direction, combination of above mentioned herbal ingredients together in a formulation, which is cosmetically acceptable, stable, easily prepared and applicable, will be useful for the skin disorders. In case of topical application of herbal substances, emulsions have offer formulation advantages due to their structure available as both aqueous and oily substances and being cosmetically acceptable [5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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Preparation and characterization of herbal emulsion formulations

Tanrıverdi¹,

Yapar²

2017

mpj

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“…Dalam penggunaan bahan baku obat dari bahan alam tidak cukup hanya berdasarkan pengalaman, tetapi juga perlu dibuktikan secara ilmiah. Beberapa tumbuhan yang telah diteliti memiliki potensi sebagai anti-aging adalah Mahkota Dewa (Shamsuddin, et al, 2018), Sirih (Muthukumarasamy & Ideris, 2016), Narwastu Narwastu (Mishra, et al, 2014), Rambutan (Sekar, et al, 2017), Jagung (Safitri, et al, 2016), Ubi Jalar (Dipahayu, et al, 2014), Kelor (Sugihartini & Nuryanti, 2017), Raspberi (Kawarkhe, et al, 2016), Anggur (Kawarkhe, et al, 2016)dan Lengkeng .…”

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Formulasi dan Evaluasi Secara Fisikokimia Sedian Krim Anti-Aging

Maya

Mutakin

2017

Maj. Farmasetika

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Penuaan secara alamiah terjadi pada makhluk hidup. Efek dari proses penuaan pada manusia adalah terjadinya gangguan secara fisik seperti kehilangan elastisitas kulit sehingga kulit menjadi keriput dan juga hiperpigmentasi. Sebagai upaya dalam mencegah maupun mengatasi hal tersebut adalah dengan menggunakan antioksidan. Antioksidan dapat menginhibisi terjadinya reaksi oksidasi sel sehingga dapat mengurangi kerusakan sel dan penuaan dini. Beberapa tumbuhan yang telah diteliti memiliki potensi sebagai antiaging adalah mahkota dewa, sirih, narwastu, rambutan, jagung, ubi jalar, kelor, raspberi, anggur dan lengkeng. Untuk memudahkan penggunaan tanaman tersebut sebagai antioksidan, bentuk sediaan kosmetik merupakan pilihan utama yang dapat digunakan secara mudah dan nyaman. Bentuk sediaan kosmetik dapat berupa sediaan gel, krim, bedak, salep dan losion. Review artikel ini akan memaparkan formulasi sediaan krim anti-aging yang mengandung zat aktif dari ekstrak tanaman. Review artikel ini menggunakan metode penelitian komparatif dengan mengumpulkan berbagi sumber pustaka primer dari 18 jurnal penelitian. Hasil review ini mengindikasikan bahwa semua krim yang diformulasikan stabil secara fisikokimia dengan tidak adanya tanda-tanda kerusakan bentuk sediaan emulsi dan perubahan sifat fisikokimia selama uji stabilitas dilaksanakan. Sehingga formula ini berpotensi digunakan dalam pengembangan formula sediaan krim yang mengandung zat aktif dari ekstrak tanaman. Kata kunci: Anti-aging, Sediaan Krim, Ekstrak

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Formulation and evaluation of herbal antioxidant face cream of Nardostachys jatamansi collected from Indian Himalayan region

Cited by 35 publications

References 2 publications

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Preparation and characterization of herbal emulsion formulations

Formulasi dan Evaluasi Secara Fisikokimia Sedian Krim Anti-Aging

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