Formulation and Evaluation of Herbal Ultrasound Gel for Ultrasonography

Preparation and Evaluation of Polymer-Based Ultrasound Gel and Its Application in Ultrasonography

“…One gram of the gel sample was applied topically to a two square inch area of the hand. Observations were taken and recorded for any irritation, lesions, redness, or edema at periodic intervals for roughly 24 h [ 11 , 13 ].…”

“…Then the plates were incubated for 24 h at 37 °C. Plates were removed after the incubation period and bacterial growth was examined by measuring the zone of inhibition using a zone reader in millimeters [ 13 , 40 ].…”

“…To eliminate any bubbles that had entrapped in the slot, the sample was stirred for 5–10 s with the probe. The sample’s conductivity values were then displayed on the meter automatically [ 13 ]. In this way, the conductivity of all samples was measured.…”

“…These ultrasound procedures utilize ultrasound waves (sound waves of a frequency greater than 20 kHz, which is the upper limit of human hearing) and use a range of frequencies (1.5–20 MHz) depending on their applications [ 10 , 11 ]. These ultrasound procedures need a special medium that can provide lubrication to the skin to aid the movement of the transducer on the skin and can replace air between the transducer and the patient’s skin because ultrasound waves have difficulty in traveling through the air due to very small acoustic impedance (0.004 MRayls) [ 12 , 13 , 14 , 15 ]. Ultrasound gel is the best medium to achieve these functions.…”

“…It also prevents the formation of stretch marks [ 30 ]. Aloe vera has synergistic activity due to its 75 active ingredients [ 13 ]. Ultrasound gels are prepared using fresh aloe vera gel, which does not irritate the skin and makes them safe for people with sensitive skin.…”