Formulation and Evaluation of Herbal Hand Sanitizer Based on Stevia (Stevia rebaudiana)

Harismah, Kun; Ariningrum, Nurul Diah; Fuadi, Ahmad; Mujiburohman, Muhammad; Mirzaei, Mahmoud

doi:10.1088/1742-6596/1858/1/012053

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…Antimicrobial activity of polyherbal hand sanitizer [18] The antimicrobial activity of the polyherbal hand sanitizer was evaluated using the agar well diffusion method against various microorganisms. The results showed that the formulation exhibited significant antimicrobial activity against all the tested microorganisms [Table 8].…”

Section: Physical Chemical and Microbiological Stability Of Formulationmentioning

confidence: 99%

Untitled

2023

IJPSCR

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The main aim for the preparation of a polyherbal hand sanitizer is for "hand hygiene." It is a vital principle in the prevention, control, and reduction of any acquired infection. Mainly hand sanitizer can stop the chain of transmission of micro-organisms and other bacteria from hand to different parts of our body. Hand hygiene is important and one of the most critical steps in food production, food service as well as in homes and other day care preparations. Hand sanitizer avoids adverse effects such as itching, irritation, and dermatitis. This study aimed to formulate a polyherbal hand sanitizer using neem, Eucalyptus, and cinnamon extracts and to evaluate its physiochemical parameters, stability, and antimicrobial activity. In conclusion, the formulated Polyherbal hand sanitizer using neem, Eucalyptus, and cinnamon extracts showed good physiochemical parameters, stability, and antimicrobial activity. The use of natural plant extracts in hand sanitizers is a promising alternative to synthetic antimicrobial agents, which may have adverse effects on human health and the environment. Further studies are warranted to evaluate the safety and efficacy of the polyherbal hand sanitizer in humans.

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Section: Physical Chemical and Microbiological Stability Of Formulationmentioning

confidence: 99%

Untitled

2023

IJPSCR

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“…Furthermore, the extract of temu hitam rhizome was dissolved in distilled water and stirred until dissolved. The soluble temu hitam rhizome extract is put into a mortar and ground homogeneously until a gel is formed [22], [23].…”

Section: Formulation Of Hand Sanitizer Gel Preparation Of Temu Hitam ...mentioning

confidence: 99%

Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

Sari

Harnis

Harahap

2022

International Journal of Science, Technology & Management

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Temu Hitam (Curcuma aeruginosa Roxb) is one of the most widely grown plants in Indonesia at an altitude of 400–750 m asl and contains many secondary metabolites, including flavonoids, alkaloids, saponins, tannins, and curcuminoids, which in the test had antibacterial activity and growth inhibitors. worm larvae in the gastrointestinal tract and the effect of increasing the body's immunity The purpose of this study was to identify the content of secondary metabolites contained in the rhizome of black turmeric, which would then be formulated into gel hand sanitizer preparations. Secondary metabolite testing was conducted on alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides. Three different hand sanitizer gel formulations were created using different extract concentrations, 5%, 10%, and 15%. Evaluation tests were then run on the preparations, including stability, organoleptic, homogeneity, pH, and dispersion tests. Alkaloids, flavonoids, tannins, saponins, and steroids were found in the temu hitam rhizome, according to the results of secondary metabolite testing. The dosage form was semi-solid, had a light brown to blackish brown hue, a distinct spice scent, was homogeneously prepared, and had a pH of 7.0, according to the examination of the formulation results 4,1 ± 0,17; 4,4 ± 0,19; 4,9 ± 0,08; 4,9 ± 0,09, viscosity 2378 ± 209,9; 3340 ± 220,7; 4509 ± 285,6; 4881 ± 276,7; and spreadability test 5; 6,2; 5,4; 4,9 cm . The conclusion of this study is that the results of the phytochemical screening of simplicia and the ethanolic extract of the Temu Hitam rhizome showed positive results, containing secondary metabolites of alkaloids, flavonoids, tannins, saponins, glycosides, and steroids/triterpenoids that can be formulated into hand sanitizer gel preparations that meet the requirements for preparation evaluation.

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“…The first use of stevia-based compounds was in food industries, but they are also considered to be therapeutic agents nowadays [7]. Accordingly, several types of investigations in all in silico, in vitro, in vivo, and clinical media have been carried out on stevia to recognize there featured activities [8][9][10][11]. Besides such therapeutic importance, a general demand has been arisen on use of stevia as a natural product in everyday life style package [12].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

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Formulation and Evaluation of Herbal Hand Sanitizer Based on Stevia (Stevia rebaudiana)

Cited by 4 publications

References 3 publications

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Phytochemical Screening and Formulation of Hand Sanitizer Gel Preparations from Temu Hitam Rhizome Extract (Curcuma aeruginosa Roxb)

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