Formulation and Development of Cephalexin Oral Reconstitutable Suspension

Sahu, Vandana Devi; Agrawal, Mukta; Sharma, Mukesh C.; Chandrakar, Sandhya; Gupta, Sujata; Sharma, Garima; Dewangan, Kalyani; Solanki, Harsha; Majumdar, Manisha; Tripathi, D. K.; Alexander, Amit; AJAZUDDIN, .

doi:10.5958/0974-360x.2016.00145.1

Cited by 4 publications

(2 citation statements)

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“…Plate-count with surface spread method was used for the enumeration of microorganisms. [15][16][17][18] This method was previously validated by a growth promotion test to ensure that one of the products present in the syrup did not inhibit the sprouts. A volume of 10 µL, of each dilution was taken and spread over 3 Petri dishes of casein soya bean digest agar and incubated at 30-35°C for 5 days.…”

Section: Microbiological Stability Evaluationmentioning

confidence: 99%

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Clinical and Stability Assessment of Chloral Hydrate Syrup for Sedation in Pediatrics

Omar¹,

Yacine²,

Karim³

et al. 2022

IJDDT

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To develop a stable chloral hydrate (CH) syrup and to test its clinical efficacy in inducing painless sedation during diagnostic imaging examinations in children under 4 years of age. For the physico-chemical tests, the vials were stored at + 5 and + 25°C and the analysis was carried out for 60 days. The microbiological tests were performed in 4 days of analysis. The prospective clinical study was conducted in 33 infants and children after receiving CH syrup orally for sedation prior to magnetic resonance imaging (MRI). After two months of storage, the average concentrations in all tests were greater than 95% of the initial chloral hydrate concentration. No microbiological growth was noted after 60 days of storage. The clinical use of syrup in children resulted in effective sedation in 100% of children and rare side effects. Compared to midazolam, chloral hydrate is more effective for sedating children under 5 years of age and is significantly less expensive. The prescription of 5% CH syrup for sedation prior to imaging diagnosis has well-established efficacy. However, the safe use of chloral hydrate in infants and children under 5 years of age should be in accordance with international recommendations.

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Section: Microbiological Stability Evaluationmentioning

confidence: 99%

“…Significance was considered when the level was less than 0.05. All tests were performed using Minitab 17 (Minitab LLC, USA).…”

Section: Clinical Study Protocolmentioning

confidence: 99%

Clinical and Stability Assessment of Chloral Hydrate Syrup for Sedation in Pediatrics

Omar¹,

Yacine²,

Karim³

et al. 2022

IJDDT

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Polymer based nanoparticles for BCS class II drugs -“A mini Review”

Mahajan

Thakur

Goswami

et al. 2022

Materials Today: Proceedings

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Resistance to Antibiotics used in Treating Gum infections: A Cross-Sectional Study based on Gum Disease Patients in Syria in the Period of Covid 19

Hassan Deeb

2024

International Journal of Innovative Science and Research Techno

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Since the mouth is the ideal habitat for the development of all types of organisms, the gums are likely to be exposed to many diseases caused by certain types of bacteria. Therefore, it is necessary to constantly search for suitable types of effective antibiotics that can eliminate gum infections. A paper research includes a set of questions. The paper research questionnaire was distributed to one hundred dentists with an average experience of no less than 9 years. The research form addressed eight antibiotics recommended for use in treating Gum infections. In a statistical analysis of doctors' answers about the most common antibiotics they use to treat gum infections, metronidazole ranked first, followed by amoxicillin and valdoxycycline. While clindamycin and ciprofloxacin ranked last. Doctors must currently commit not to prescribe antibiotics when there is a possibility of a patient's spontaneous recovery, for fear of incorrect use of antibiotics, which leads to an increase in the spread of bacterial resistance.

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Formulation and Development of Cephalexin Oral Reconstitutable Suspension

Cited by 4 publications

References 0 publications

Clinical and Stability Assessment of Chloral Hydrate Syrup for Sedation in Pediatrics

Clinical and Stability Assessment of Chloral Hydrate Syrup for Sedation in Pediatrics

Polymer based nanoparticles for BCS class II drugs -“A mini Review”

Resistance to Antibiotics used in Treating Gum infections: A Cross-Sectional Study based on Gum Disease Patients in Syria in the Period of Covid 19

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