Formulation and characterization of chitosan hydrochloride and carboxymethyl chitosan encapsulated quercetin nanoparticles for controlled applications in foods system and simulated gastrointestinal condition

Yan, Ling; Wang, Rongrong; Wang, Huimin; Sheng, Kangliang; Liu, Changhong; Qu, Hao; Ma, Aijin; Lu, Zheng

doi:10.1016/j.foodhyd.2018.06.025

Cited by 59 publications

(37 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A similar release and stabilization behavior was observed between the results reported by Yan et al. () and those previously analyzed from Liang et al. ().…”

Section: Scps In Foodsupporting

confidence: 90%

“…QUE-loaded Cs derivative NPs were self-assembled mainly by electrostatic and H-bonding interactions ( Figure 2). A similar release and stabilization behavior was observed between the results reported by Yan et al (2018) and those previously analyzed from Liang et al (2017). As expected, Cs NPs without load had a smaller particle size compared to QUEloaded systems.…”

Section: Self-assembled Chitin and Cssupporting

confidence: 88%

“…In this same line, Yan et al. () encapsulated quercetin (QUE––active compound little water soluble, stable, and bioavailable) into Cs NPs obtained from Cs derivatives: Cs hydrochloride and carboxymethylated Cs (Figure ). QUE‐loaded Cs derivative NPs were self‐assembled mainly by electrostatic and H‐bonding interactions (Figure ).…”

Section: Scps In Foodmentioning

confidence: 97%

“…The authors concluded in this work that the antioxidant activity (2,2-diphenyl-1-picrylhydrazyl (DPPH•) radical scavenging activity) shown by EGCG-loaded self-assembled nanospheres (diameter approximately 100 to 200 nm) can be used as food additives for the inhibition of lipid oxidation in fatty foods, thus improving the food quality. In this same line, Yan et al (2018) encapsulated quercetin (QUE--active compound little water soluble, stable, and bioavailable) into Cs NPs obtained from Cs derivatives: Cs hydrochloride and carboxymethylated Cs ( Figure 2). QUE-loaded Cs derivative NPs were self-assembled mainly by electrostatic and H-bonding interactions ( Figure 2).…”

Section: Self-assembled Chitin and Csmentioning

confidence: 97%

“…As expected, Cs NPs without load had a smaller particle size compared to QUE‐loaded systems. A sinusoidal particle size distribution also suggested that a single encapsulation mechanism in the SCP was given, and the release of the active compound under simulated gastrointestinal conditions demonstrated the potential of these self‐assembled systems for the development of functional foods and dietary supplements with improved water solubility (Yan et al., ).…”

Section: Scps In Foodmentioning

confidence: 99%

See 4 more Smart Citations

Self‐Assembled Carbohydrate Polymers for Food Applications: A Review

Valencia

Zare‬

Makvandi

et al. 2019

Comp Rev Food Sci Food Safe

View full text Add to dashboard Cite

The self‐assembled natural and synthetic polymers are booming. However, natural polymers obtained from native or modified carbohydrate polymers (CPs), such as celluloses, chitosan, glucans, gums, pectins, and starches, have had special attention as raw material in the manufacture of self‐assembled polymer composite materials having several forms: films, hydrogels, micelles, and particles. The easy manipulation of the architecture of the CPs, as well as their high availability in nature, low cost, and being sustainable and green polymers have been the main positive points in the use of them for different applications. CPs have been used as building blocks for composite structures, and their easy orientation and ordering has given rise to self‐assembled CPs (SCPs). These macromolecules have been little studied for food applications. Nonetheless, their research has grown mainly in the last 5 years as encapsulated food additive wall materials, food coatings, and edible films. The multifaceted properties (systems sensitive to pH, temperature, ionic strength, types of ions, mechanical force, and enzymes) of these devices are leading to the development of advanced food materials. This review article focused on the analysis of SCPs for food applications in order to encourage other research groups for their preparation and implementation.

show abstract

“…A similar release and stabilization behavior was observed between the results reported by Yan et al. () and those previously analyzed from Liang et al. ().…”

Section: Scps In Foodsupporting

confidence: 90%

Section: Self-assembled Chitin and Cssupporting

confidence: 88%

Section: Scps In Foodmentioning

confidence: 97%

Section: Self-assembled Chitin and Csmentioning

confidence: 97%

Section: Scps In Foodmentioning

confidence: 99%

See 3 more Smart Citations

Self‐Assembled Carbohydrate Polymers for Food Applications: A Review

Valencia

Zare‬

Makvandi

et al. 2019

Comp Rev Food Sci Food Safe

View full text Add to dashboard Cite

show abstract

Interactions of plant food bioactives‐loaded nano delivery systems at the nano‐bio interface and its pharmacokinetics: An overview

et al. 2022

View full text Add to dashboard Cite

Plant food bioactives (PFBs) offer immense health benefits with a greater scope for treating various life‐threatening diseases and lifestyle disorders. Knowing their therapeutic potentials, a lot of research works are being carried out on formulating PFBs‐loaded nano delivery systems (NDSs) to enhance their bioefficacy. However, limited information are available on the interactions occurring at the nano‐bio interface. Therefore, studies on nano‐bio interactions are of immense importance towards designing/formulating effective NDSs for PFBs. Understanding the significance of nano‐bio interface of food bioactive‐loaded NDSs would help us to predict the formation of biocorona as well as the correlation between the nanoparticles and their surrounding environments that are influenced by the NDS's physicochemical properties. The physicochemical characteristics of NDSs like size, shape, and surface charge will decide their fate in the biological fluids and have been discussed in detail. As the bioactives‐loaded NDS enters the gastrointestinal tract, formation of biocorona including protein and enzyme corona at the nano‐bio interface will takes place. Subsequently, the fate of PFBs‐loaded NDSs influences the absorption, distribution, metabolism, and excretion (ADME) processes and thereby its bioavailability, bioefficacy, and biosafety. The current review focuses on understanding the journey of PBFs‐loaded NDSs, the nature of interactions happening at nano‐bio interface, and its pharmacokinetics properties. In addition, a specific case study approach on curcumin‐loaded NDSs, and its reported interactions at nano‐bio interface, including ADME mechanism are comprehensively presented.

show abstract

Carboxymethyl Chitosan-Based Materials in Packaging, Food, Pharmaceutical, and Cosmetics

Rachtanapun,

Jantrawut

et al. 2023

Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications

View full text Add to dashboard Cite

Formulation and characterization of chitosan hydrochloride and carboxymethyl chitosan encapsulated quercetin nanoparticles for controlled applications in foods system and simulated gastrointestinal condition

Cited by 59 publications

References 36 publications

Self‐Assembled Carbohydrate Polymers for Food Applications: A Review

Self‐Assembled Carbohydrate Polymers for Food Applications: A Review

Interactions of plant food bioactives‐loaded nano delivery systems at the nano‐bio interface and its pharmacokinetics: An overview

Carboxymethyl Chitosan-Based Materials in Packaging, Food, Pharmaceutical, and Cosmetics

Contact Info

Product

Resources

About