Formulation and Biodegradation of Surface-Supported Biopolymer-Based Microgels Formed via Hard Templating onto Vaterite CaCO3 Crystals
Mariam Mammen,
Cain Hogg,
Dominic Craske
et al.
Abstract:In recent decades, there has been increased attention to the role of layer-by-layer assembled bio-polymer 3D structures (capsules, beads, and microgels) for biomedical applications. Such free-standing multilayer structures are formed via hard templating onto sacrificial cores such as vaterite CaCO3 crystals. Immobilization of these structures onto solid surfaces (e.g., implants and catheters) opens the way for the formulation of advanced bio-coating with a patterned surface. However, the immobilization step is… Show more
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